Results 61 to 70 of about 871,984 (313)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Estimation and simulation in directional and statistical shape models [PDF]

open access: yes, 2012
This thesis is concerned with problems in two related areas of statistical shape analysis in two dimensional landmarks data and directional statistics in various sample spaces.
Ganeiber, Asaad Mohammed
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Silhouette-based gait recognition using Procrustes shape analysis and elliptic Fourier descriptors [PDF]

open access: yes, 2012
This paper presents a gait recognition method which combines spatio-temporal motion characteristics, statistical and physical parameters (referred to as STM-SPP) of a human subject for its classification by analysing shape of the subject's silhouette ...
Tjahjadi, Tardi, Das Choudhury, Sruti
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Robust Rigid Shape Registration Method Using a Level Set Formulation

open access: yes, 2010
This paper presents a fast algorithm for robust registration of shapes implicitly represented by signed distance functions(SDF). The proposed algorithm aims to recover the transformation parameters( scaling, rotation, and translation) by minimizing the ...
Mark S. Nixon   +5 more
core   +1 more source

A novel shape optimization method using knot insertion algorithm in B-spline and its application to transonic airfoil design [PDF]

open access: yes, 2011
A new method using the cubic B-spline curves with nominal uniform knot set to parameterize the geometry is proposed to deal with shape optimization problems.
Xu, B.   +3 more
core   +1 more source

Pavement Crack Detection from Mobile Laser Scanning Point Clouds Using a Time Grid

open access: yesSensors, 2020
This paper presents a novel algorithm for detecting pavement cracks from mobile laser scanning (MLS) data. The algorithm losslessly transforms MLS data into a regular grid structure to adopt the proven image-based methods of crack extraction.
Mianqing Zhong   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A machine learning approach to statistical shape models with applications to medical image analysis [PDF]

open access: yes, 2010
Statistical shape models have become an indispensable tool for image analysis. The use of shape models is especially popular in computer vision and medical image analysis, where they were incorporated as a prior into a wide range of different algorithms.
Lüthi, Marcel
core   +1 more source

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