Results 71 to 80 of about 769,155 (267)

Impact of cavity shape on thermal accelerometer parameters

open access: yesMicro and Nano Engineering
This publication examines CFD (Computational Fluid Dynamics) analyses of a uniaxial accelerometer's behavior, focusing on convective heat transfer. A thermal convective accelerometer is a sensor that employs hot wire technology to quantify acceleration ...
Toulmé Valentin   +4 more
doaj   +1 more source

Combined shape and non-shape sensitivity for optimal design of metal forming operations

open access: yesComputer Assisted Methods in Engineering and Science, 2023
Shape and non-shape optimization is carried out for metal forming processes. This means a unified treatment of both shape parameters and other process parameters which are assumed to be design variables.
Horacio J. Antunez, Maciej Kowalczyk
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Effect of different combinations of size and shape parameters in the percentage error of classification of structural elements in vegetal tissue of the pumpkin Cucurbita pepo L. using probabilistic neural networks

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2016
The optimal combination of size and shape parameters for classifying structural elements with the lowest percentage error is determined. For this purpose, logical sequences and a series of micrographs of tissues of the pumpkin Cucurbita pepo L.
Jimy Frank Oblitas-Cruz   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

One-Sided Confidence Interval Estimation for Weibull Shape and Scale Parameters

open access: yesRevista de Matemática: Teoría y Aplicaciones, 2012
In this paper, we consider the problem of one-sided conditional and unconditional interval estimation for the scale and shape parameters in a two-parameter Weibull model. The statistical inference is based upon the pivots advocated in Bain and Engelhardt,
Smail Mahdi
doaj   +1 more source

The shape parameters of coal and gangue particles derived from 3D scanning. [PDF]

open access: yesSci Data, 2023
Yang D   +5 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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