Results 111 to 120 of about 3,563,944 (406)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Shared Care, Elder and Family Member Skills Used to Manage Burden [PDF]
, 2005 Aim. The aim of this paper is to further develop the construct of Shared Care by comparing and contrasting it to related research, and to show how the construct can be used to guide research and practice. Background.
AhYun K. +28 more
core +2 more sources
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Clinical decision making and outcome in the routine care of people with severe mental illness across Europe (CEDAR) [PDF]
, 2015 Aims. There is a lack of knowledge on clinical decision making and its relation to outcome in the routine treatment of people with severe mental illness.
A. Fiorillo +13 more
core +2 more sources
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Approaches to decision-making among late-stage melanoma patients: a multifactorial investigation. [PDF]
, 2019 PurposeThe treatment decisions of melanoma patients are poorly understood. Most research on cancer patient decision-making focuses on limited components of specific treatment decisions.
Abramson, Corey M +3 more
core
The past and future of the AHP in health care decision making [PDF]
, 2011 Objective. Health care decision making is a complex process involving many stakeholders and allowing for multiple decision criteria. The Analytic Hierarchy process (AHP) can support these complex decisions that relate to the application and coverage of ...
Hummel, Marjan, IJzerman, Maarten
core +2 more sources
Surgeons’ Views on Shared Decision-Making
Journal of Patient-Centered Research and Reviews, 2020 Purpose: Shared decision-making (SDM) has a significant role in surgical encounters, where decisions are influenced by both clinician and patient preferences. Herein, we sought to explore surgeons’ practices and beliefs about SDM. Methods: We performed a
Suraj Kannan +5 more
doaj +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Child and Adolescent Psychiatry and Mental Health, 2020 Background Most mental health problems occur in adolescence. There is increasing recognition of user participation and shared decision-making in adolescents’ mental healthcare. However, research in this field of clinical practice is still sparse.
Stig Bjønness +3 more
semanticscholar +1 more source