Results 111 to 120 of about 2,296,903 (345)

External validation of a risk stratification model to assist shared decision making for patients starting renal replacement therapy [PDF]

, 2016
BACKGROUND: Shared decision making is nowadays acknowledged as an essential step when deciding on starting renal replacement therapy. Valid risk stratification of prognosis is, besides discussing quality of life, crucial in this regard.
De Meester, Johan, De Moor, Bart, Lemahieu, Wim, Peeters, Patrick, Van Biesen, Wim, Veys, Nic   +5 more
core   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

POS1404 SHARED DECISION MAKING AND INTERNET USE FOR GATHERING HEALTH INFORMATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: A MULTICENTER CROSS-SECTIONAL STUDY [PDF]

, 2022
Takanori Ichikawa, Y. Shimojima, D. Kishida, N. Yajima, R. Yoshimi, K. E. Sada, Y. Miyawaki, N. Oguro, N. Sakurai, C. Hidekawa, K. Hayashi, K. Shidahara, Y. Ishikawa, Y. Sekijima, N. Kurita   +14 more
openalex   +1 more source

Preferences of patients with advanced lung cancer regarding the involvement of family and others in medical decision-making [PDF]

, 2010
Objective: To explore the preferences of competent patients with advanced lung cancer regarding involvement of family and/or others in their medical decision-making, and their future preferences in case of loss of competence.
Bernheim, Jan L, Bossuyt, Nathalie, Deliens, Luc, Deschepper, Reginald, Galdermans, Daniella, Germonpré, Paul, Mortier, Freddy, Pardon, Koen, Schallier, Denis, Van Kerckhoven, Willem, Vander Stichele, Robert   +10 more
core   +3 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The relationship between shared decision-making and health-related quality of life among patients in Hong Kong SAR, China [PDF]

, 2017
Richard Huan Xu, Annie Wai Ling Cheung, Eliza Lai‐Yi Wong   +2 more
openalex   +1 more source

COVID-19 in Women's health: Pre-operative gynaecological assessment and shared decision making

, 2021
Elizabeth Ball, Fredric Willmott, Carol Rivas, Chiraag Talati   +3 more
openalex   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Implementing shared decision making in routine mental health care [PDF]

, 2017
Shared decision making (SDM) in mental health care involves clinicians and patients working together to make decisions. The key elements of SDM have been identified, decision support tools have been developed, and SDM has been recommended in mental ...
Anonymous, Beauchamp, Bär Deucher, Campbell, Charles, Chewning, Clarke, Clever, Cornuz, Corrigan, Coulter, Coulter, Crumlish, Daley, Davidson, Deegan, Del Piccolo, Dibb, Dixon, Drake, Duncan, Eliacin, Elwyn, Farrelly, Feldman-Stewart, First, Freidl, French, Fukui, Galderisi, Goffman, Gordon, Hamann, Hamann, Hamann, Hamann, Hamann, Hamann, Hamann, Hamann, Hanlon, Harper, Hauser, Health, Henderson, Henderson, Holmes-Rovner, Hölzel, Ito, Joosten, Joosten, Joosten, Kaminskiy, Karnieli-Miller, Kidd, Knaup, Konrad, las Cuevas, Le Boutillier, Le Boutillier, Le Boutillier, Leamy, Legare, Loh, Ludman, Mahlke, Makoul, Malm, McCabe, McGeorge, McGregor, McGuire, Mental Health “Recovery” Study Working Group, Metz, Moher, Morant, Moumjid, Okasha, Perestelo-Perez, Peters, Pilgrim, Puschner, Puschner, Puschner, Quirk, Razzouk, Schattner, Scholl, Seale, Semrau, Shepherd, Slade, Slade, Slade, Slade, Stacey, Thompson, Thornicroft, Thornicroft, Wakefield, Watson, Wild, Woltmann, Zipursky   +103 more
core   +2 more sources