Results 61 to 70 of about 755,905 (296)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Anti-Primacy: Sharing Power in American Corporations [PDF]

open access: yes, 2015
Prominent theories of corporate governance frequently adopt primacy as an organizing theme. Shareholder primacy is the oldest and most used of this genre. Director primacy has grown dramatically, presenting in at least two distinct versions. A variety of
Thompson, Robert B.
core   +3 more sources

Sharing a Government

open access: yes, 2019
This paper develops a simple theoretical framework to study a set of regions, each with its own regional government, who share a union or central government. These governments must decide whether to implement or discard a large number of projects that produce local beneÖts for the region that implements them, and externalities for the rest of the ...
openaire   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Tools for Data Governance

open access: yesTechnology and Regulation, 2020
This article describes the challenges of data governance in terms of the broader framework of knowledge commons governance, an institutional approach to gov- erning shared knowledge, information, and data resources.
Michael Madison
doaj   +1 more source

Hutcheson Medical Center: Focusing on Personal Interactions [PDF]

open access: yes, 2008
Outlines elements of a strategy for high patient satisfaction focused on patient-staff interactions and patients' needs, including a culture of customer service, shared governance, better data collection, more visible leaders, and evidence-based ...
Sharon Silow-Carroll
core  

Sharing the Burden of Collective Security in the European Union. Research Note [PDF]

open access: yes, 2009
This article compares European Union (EU) burden-sharing in security governance distinguishing between assurance, prevention, protection, and compellence policies.
Arce M.   +12 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Shared services – shared necessity: Austerity, reformed local government and reduced budgets1

open access: yesAdministration, 2015
Shared services are now established as a core delivery model in local and regional governance arrangements. Shared services have emerged as a ‘common sense’ delivery vehicle with attendant efficiency and effectiveness gains.
Lloyd Greg
doaj   +1 more source

Network governance theory as basic pattern for promoting financial support system of the poor in Iranian health system

open access: yesBMC Health Services Research, 2021
Background The share of out-of-pocket payments in Iranian families has the greatest burden on the poor and lead to an impoverishment caused by catastrophic health expenditures.
Manal Etemadi   +4 more
doaj   +1 more source

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