Results 121 to 130 of about 610,575 (253)

Complex Economic Systems: Using Collective Intentionality Analysis to Explain Individual ldentity in Networks [PDF]

, 2004
Une approche particulière de l\u27analyse de économies vues comme des systèmes complexes étudie l\u27interaction entre les individus dans des réseaus locaux ou de voisinage qui sont un sous-ensemble des économies plus larges.
Davis, John B.
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

The Agent Intellect as “form for us” and Averroes’s Critique of al-Fârâbî [PDF]

, 2005
This article explicates Averroes\u27s understanding of human knowing and abstraction in this three commentaries on Aristotle\u27s De Anima. While Averroes\u27s views on the nature of the human material intellect changes through the three commentaries ...
Taylor, Richard C.
core   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Parenting for sustainability: a moderated mediation study on adolescent purchase intentions

International Journal of Adolescence and Youth
Despite rising interest in sustainable fashion in India, little is known about how parental factors shape adolescents’ sustainable purchase intentions—particularly within urban, educated Indian families. This study explores how parental factors influence
Kavitha Venkatasubramany Iyer, Siya Ragade   +1 more
doaj   +1 more source

Assessment for learning and for self-regulation [PDF]

, 2015
Drawing on a research study of formative assessment practices in Irish schools, this paper traces the design, development and pilot of the Assessment for Learning Audit instrument (AfLAi) - a research tool for measuring teachers’ understanding and ...
Lysaght, Zita
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Dataset of the relationship between authentic virtual reality experiences and tourists’ visiting intentionsMendeley Data

Data in Brief
After the pandemic, the demand for a rapid recovery of tourism has led to increased intense competition among destinations, posing a considerable challenge for tourism managers and destination marketers worldwide.
Thi Bich Thuy Nguyen, Quoc Vinh Pham-Le, Ngoc Tuan Chau   +2 more
doaj   +1 more source