Results 131 to 140 of about 610,575 (253)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Factors Influencing Sustained Use of Shared E-Scooter Services in Urban Taiwan
Promet (Zagreb)This study investigates the factors that drive users to sustain their usage of shared electric scooter (e-scooter) services in Taiwan, distinguishing itself from the conventional focus on predicting consumers’ initial adoption and behavioural intentions.
Fei-Hui HUANG
doaj +1 more source
Trust and attitude in consumer food choices under risk [PDF]
In this paper, attitude and trust are studied in the context of a food scare (dioxin) with the aim of identifying the components of attitude and trust that significantly affect how purchases are determined. A revised version of the model by MAYER et al. (
Bonini, Nicolao +5 more
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Back to where we came from: evolutionary psychology and children’s literature and media [PDF]
, 2017 In 2010, The New York Times ran an article which announced that ‘the next big thing in English [Studies]’ was ‘using evolutionary theory to explain fiction’.
Cocks, Neil, Lesnik-Oberstein, Karin
core
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
The relation between language and theory of mind in development and evolution [PDF]
, 2002 Considering the close relation between language and theory of mind in development and their tight connection in social behavior, it is no big leap to claim that the two capacities have been related in evolution as well.
Malle, Bertram F.
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Into the Fray: Novice Teachers Tackle Standards-Based Mathematics [PDF]
, 2007 This article tracks twenty-one graduates of a refom-based mathematics teacher education program for two years as they begin teaching mathematics in public elementary schools in New York City.
Gningue, S., Schroder, B.
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source