Results 41 to 50 of about 16,687 (260)

Processes governing the flow redistribution in sharp river bends [PDF]

Geomorphology, 2012
article i nfo Insight is provided in hydrodynamic processes governing the velocity redistribution in sharp river bends based on simulations of three recent experiments by means of Blanckaert and de Vriend's (2003, 2010) reduced-order nonlinear model without curvature restrictions.
Ottevanger, Willem, Blanckaert, Koen, Uijttewaal, Wim S.J.   +2 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experiments on turbulence and near bank vorticities in an open channel sharp bend

E3S Web of Conferences, 2018
Turbulence has a significant influence on fluvial processes. Especially in the sharp bends of geometrically complex natural streams, the interaction of turbulence and flow three-dimensionalities is considerable.
Farhadi Alireza, Sindelar Christine, Tritthart Michael, Habersack Helmut   +3 more
doaj   +1 more source

Turbulence structure in sharp open-channel bends

Journal of Fluid Mechanics, 2005
In spite of its practical relevance, little is known about the turbulence characteristics in sharp open-channel bends, which may largely be attributed to a lack of accurate experimental data. This paper reports an experimental investigation of the turbulence structure in one cross-section of an open-channel bend.
Blanckaert, Koen Jacques Ferdinand, De Vriend, Huib J.   +1 more
openaire   +6 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Physical Model Study of Natural Meander Cutoff in the Lower Jingjiang River [PDF]

长江科学院院报
[Objective] Continuous sharp bends in river channels are prone to significant river regime adjustments and abrupt changes under the impact of unsaturated sediment-laden flow, which have far-reaching implications for flood control, navigation, and water ...
LIU Ya, YAO Shi-ming, GUO Xiao-hu, XIE Si-quan
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Use of a stiff guidewire in transjugular liver biopsy in patients with a pronounced angle of the suprahepatic veins

Annals of Hepatology, 2004
In the performance of a transvascular liver biopsy, the Trucut-type transjugular liver biopsy set is advance over a multipurpose catheter place in the suprahepatic vein.
Andrés de Hoyos, Ma Lilia Loredo, Marco A. Martínez, Manuel R. Gil   +3 more
doaj   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source