Results 41 to 50 of about 1,925,346 (295)

Beams with the transverse-only intensity at the focus

open access: yesКомпьютерная оптика
In this work, sharp focusing of vector beams with azimuthal polarization and beams with V-line of polarization uncertainty is simulated numerically using the Richards-Wolf formulas.
S.S. Stafeev, N.N. Kazakov, V.V. Kotlyar
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The aqueous supramolecular chemistry of crown ethers

open access: yesFrontiers in Chemistry, 2023
This mini-review summarizes the seminal exploration of aqueous supramolecular chemistry of crown ether macrocycles. In history, most research of crown ethers were focusing on their supramolecular chemistry in organic phase or in gas phase.
Zhenhui Qi   +8 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Helicity of Poincaré beams at the sharp focus

open access: yesКомпьютерная оптика
In this study, helicity of Poincaré beams was considered from the point of view of the Richards-Wolf formalism. It was shown that helicity for Poincaré beams always has radial symmetry and does not depend on the azimuthal angle of the beam.
S.S. Stafeev, V.D. Zaitsev
doaj   +1 more source

Sharp focusing of light using a planar gradient microlens

open access: yesComputer Optics, 2016
It is shown numerically that using planar gradient microlenses, the coherent radiation can be focused in a narrow line of width λ/38 and length λ/5.5. The efficiency of focusing is 22%. A slitted photonic-crystal lens retains the properties of sharp focusing of light characteristic of a gradient lens.
A. Nalimov, V. Kotlyar
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Optical System Design of Oblique Airborne-Mapping Camera with Focusing Function

open access: yesPhotonics, 2022
The use of airborne-mapping technology plays a key role in the acquisition of large-scale basic geographic data information, especially in various important civil/military-mapping missions. However, most airborne-mapping cameras are limited by parameters,
Hongwei Zhang   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Focusing a Vortex Laser Beam with Polarization Conversion

open access: yesPhotonics, 2021
We show that when strongly focusing a linearly polarized optical vortex with the topological charge 2 (or −2) in the near-focus region, there occurs not only a reverse energy flow (where the projection of the Poynting vector is negative) but the right ...
Victor V. Kotlyar   +2 more
doaj   +1 more source

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