Results 51 to 60 of about 1,925,346 (295)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Characteristics of sharp focusing of vortex Laguerre-Gaussian beams

open access: yesComputer Optics, 2015
We investigate the intensity distribution of sharply focused Laguerre-Gaussian beams in relation to the uniform (linear and circular) polarization of the beam and the order of the vortex phase. It is shown that to the greatest extent the polarization state affects the longitudinal component of the electric vector of the light field. The greatest visual
D. Savelyev, S. Khonina
openaire   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Dan Sharp [PDF]

open access: yes, 2023
Dan Sharp is the child nutrition director in Grand Junction, Colorado.https://egrove.olemiss.edu/icn_ohistories/1208/thumbnail ...
Sharp, Dan
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

alexanderuernst/SHARP: SHARP

open access: yes, 2022
Full Changelog: https://github.com/alexanderuernst/SHARP/commits/v1.0.
Alexander Ulrich Ernst
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Regularized magnetotelluric inversion based on a minimum support gradient stabilizing functional

open access: yesEarth, Planets and Space, 2017
Regularization is used to solve the ill-posed problem of magnetotelluric inversion usually by adding a stabilizing functional to the objective functional that allows us to obtain a stable solution.
Yang Xiang   +4 more
doaj   +1 more source

Evaluation of sharpness measures and search algorithms for the auto focusing of high-magnification images [PDF]

open access: yesSPIE Proceedings, 2006
Digital imaging systems with extreme zoom capabilities are traditionally found in astronomy and wild life monitoring. More recently, the need for such capabilities has extended to long range surveillance and wide area monitoring such as forest fires, airport perimeters, harbors, and waterways.
Yi Yao   +3 more
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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