Results 71 to 80 of about 86,685 (296)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Reconstructing initial data using observers: error analysis of the semi-discrete and fully discrete approximations [PDF]
, 2010 A new iterative algorithm for solving initial data inverse problems from partial observations has been recently proposed in Ramdani et al. (Automatica 46(10), 1616-1625, 2010 ).
Karim Ramdani +3 more
core +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Targeting the Intrinsic Apoptosis Pathway: A Window of Opportunity for Prostate Cancer.
, 2021 Despite major improvements in the management of advanced prostate cancer over the last 20 years, the disease remains invariably fatal, and new effective therapies are required. The development of novel hormonal agents and taxane chemotherapy has improved
Balk, SP +6 more
core +1 more source
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
David Sharp, Concert Lecture Series Presentation on Abstract Art, 1963
, 1963 David Sharp began his tenure with Eastern Michigan University in 1962 as a member of the Art Department, and served until his retirement in 1995. In this presentation for the EMU Concert Lecture Series, Sharp outlines the importance of abstract art ...
Sharp, David
core
IEEE Access, 2020 The demonstration of enhanced spatial control of nanosecond microwave plasmas generated by the time reversal plasma source is presented in this paper. This new microwave plasma source relies on the spatio-temporal control of the electric field inside an ...
Valentin Mazieres +8 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Experimental demonstration of a sharp quantum Hall edge
, 2004 This article highlights the history of the quantum Hall edge, focusing on the distinction between sharp and smooth edges. We then introduce an edge-tunneling geometry consisting of two orthogonal quantum wells wherein magneto-tunneling measurements at a ...
Grayson, M. +6 more
core +1 more source
Advances in Nonlinear AnalysisThis paper examines the focusing nonlinear Schrödinger equation with an inverse-square potential in RN(N≥3) ${\mathbb{R}}^{N} \left(N\ge 3\right)$ , where the nonlinear exponent lies between the mass-critical and energy-subcritical regimes.
Lin Qiang, Chen Shaohua
doaj +1 more source