Results 51 to 60 of about 395,614 (300)

Analytical modeling of reinforced concrete columns subjected to bidirectional shear [PDF]

open access: yes, 2017
Under general seismic loading, reinforced concrete columns may be subjected to lateral loads in more than one direction. Available experimental data on columns subjected to bidirectional forces indicate that higher levels of damage and a higher loss of ...
Bairán García, Jesús Miguel   +2 more
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Shear Capacity Contribution of Steel Fiber Reinforced High-Strength Concrete Compared with and without Stirrup

open access: yesInternational Journal of Concrete Structures and Materials, 2020
This study presents the shear capacity of eco-friendly high-strength concrete (HSC) beams reinforced by 0.75% (by volume) of hooked steel fibers or shear stirrups with various spacings. Five large-scale HSC beams with steel fibers or stirrups were tested
Tian-Feng Yuan   +3 more
doaj   +1 more source

SHALLOW FLAT SOFFIT PRECAST CONCRETE FLOOR SYSTEM [PDF]

open access: yes, 2014
A precast concrete floor system that eliminates the need for column corbels and beam ledges while being very shallow. The main advantages of the present system include a span to-depth ratio of 30, a flat soffit, economy, consistency with prevailing ...
Morcous, George, Tadros, Maher
core   +1 more source

A practice-oriented approach for the assessment of brittle failures in existing reinforced concrete elements [PDF]

open access: yes, 2013
A practice-oriented approach was used to assess shear failures in existing reinforced concrete (RC) elements. A simple tool, in form of non-dimensional domains, is obtained considering the capacity models suggested by European and Italian codes.
De Luca, Flavia, Verderame, Gerardo M.
core   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Low temperature heat capacity of severely deformed metallic glass

open access: yes, 2014
The low temperature heat capacity of amorphous materials reveals a low-frequency enhancement (boson peak) of the vibrational density of states, as compared with the Debye law.
Albe, Karsten   +5 more
core   +1 more source

Strut-and-tie model based on crack band theory for deep beams [PDF]

open access: yes, 2010
yesA simplified strut-and-tie model including size effect based on the crack band theory is proposed to evaluate the shear capacity of deep beams. Concrete struts are idealized as uniformly tapered prismatic members with a stress relief strip whereas ...
Ashraf F. Ashour   +13 more
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Shear Capacity and Failure Behavior of Steel-Reinforced High Ductile Concrete Beams

open access: yesAdvances in Materials Science and Engineering, 2015
The shear behavior of six high ductile fiber reinforced concrete (HDC) beams is studied to investigate the influence of shear-span ratio and HDC mechanical property on the improvement of the shear failure mode and shear capacity of short beams.
Mingke Deng   +3 more
doaj   +1 more source

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