Results 221 to 230 of about 147,878 (274)

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Effects of manufacturing modality, primer, and adhesive polymerization on the shear bond strength of customized lingual brackets to glazed zirconia: An in vitro study. [PDF]

PLoS One
Nguyen VA, Pham NTM, Tran MN, Ha TBN, Vuong TQT.   +4 more
europepmc   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

A Multiaxial Fatigue Life Prediction Approach Accounting for Additional Strengthening Effect Based on Energy-Critical Plane Model. [PDF]

Materials (Basel)
Wang B, Gao J, Yuan Y, Zhou J, Cheng Q, Pan R.   +5 more
europepmc   +1 more source

Subvoxel Control of Fiber Orientation via Multidirectional Shearing in 3D Printing

Advanced Science, EarlyView.
A novel 3D printing technique enables subvoxel control of fiber orientation in all three directions through multidirectional shearing using nozzle rotation and inclination. It allows localized and tunable mechanical and thermal responses through programmable microstructures within a strand.
Berin Šeta, Marco Brander, Michael Sandberg, Md. Tusher Mollah, Vipin Kumar, Jon Spangenberg   +5 more
wiley   +1 more source

Three-dimensional modeling of flow through microvascular beds and surrounding interstitial spaces. [PDF]

Bioeng Transl Med
Rajeeva Pandian NK, Farrell A, Davis E, Sundaram S, van Steen ACI, Teo JLC, Eyckmans J, Chen CS.   +7 more
europepmc   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Coupling Effects of CO₂ and Thermal Treatment on the Rheological Behavior of Heavy Oil: An Integrated Experimental and Modeling Study. [PDF]

ACS Omega
Li Q, Li Y, Yuan C, Liu Z, Wang Z, Cao J, Zhang Y.   +6 more
europepmc   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source

High-intensity helical flow: a double-edged sword in coronary artery haemodynamics. [PDF]

R Soc Open Sci
Shen C, Zhang M, Keramati H, Ferreira de Almeida D, Beier S.   +4 more
europepmc   +1 more source