Results 31 to 40 of about 753,198 (298)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A constitutive model for simple shear of dense frictional suspensions
, 2017 Discrete particle simulations are used to study the shear rheology of dense, stabilized, frictional particulate suspensions in a viscous liquid, toward development of a constitutive model for steady shear flows at arbitrary stress.
Denn, Morton M. +3 more
core +1 more source
Shear stresses in shock-compressed diamond from density functional theory [PDF]
, 2008 We report density functional theory (DFT) results for the shear stresses of uniaxially compressed diamond under conditions corresponding to strong shock wave compression.
Elert, Mark L. +4 more
core +1 more source
Effects of Groove Feature on Shear Behavior of Steel-Sand Interface
Advances in Civil Engineering, 2020 Surface groove morphology of structure and particle distribution of soil had a significant effect on the surface friction of structure. In order to investigate the interface shear stress-shear displacement curves, interface model and interface shear ...
Jukun Guo +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Describing the Flow Curve of Shear-Banding Fluids Through a Structural Minimal Model [PDF]
, 2009 Main characteristics of colloidal systems that develop fluid phases with different mechanical properties, namely shear-banding fluids, are briefly reviewed both from experimental and theoretical (modelling) point of view. A non-monotonic shear stress vs.
Berli, Claudio, Quemada, Daniel
core +2 more sources
A machine learning-based method for predicting the shear behaviors of rock joints
Soils and FoundationsIn this study, machine learning prediction models (MLPMs), including artificial neural network (ANN), support vector regression (SVR), K-nearest neighbors (KNN), and random forest (RF) algorithms, were developed to predict the peak shear stress values ...
Liu He +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Activated dynamics and effective temperature in a steady state sheared glass
, 2007 We conduct nonequilibrium molecular dynamics simulations to measure the shear stress, the average inherent structure energy, and the effective temperature $T_{eff}$ of a sheared model glass as a function of bath temperature $T$ and shear strain rate. For
Andrea J. Liu +3 more
core +1 more source
Shear-stress relaxation and ensemble transformation of shear-stress autocorrelation functions [PDF]
Physical Review E, 2015 We revisit the relation between the shear stress relaxation modulus $G(t)$, computed at finite shear strain $0 < \ll 1$, and the shear stress autocorrelation functions $C(t)|_ $ and $C(t)|_ $ computed, respectively, at imposed strain $ $ and mean stress $ $.
Wittmer, J. P., Xu, Hong, Baschnagel, J.
openaire +4 more sources