Results 91 to 100 of about 1,162,244 (382)
罕见病研究Recently, adeno-associated virus(AAV)vectors have been a hotspot in gene therapy and have shown great potential for rare diseases therapy, due to their low pathogenicity, mild immunogenicity and high tissue specificity.
REN Jianwei, ZHENG Xin, HAN Xiaohong
doaj +1 more source
Optimal control of circular cylinder wakes using long control horizons [PDF]
, 2015 The classical problem of suppressing vortex shedding in the wake of a circular cylinder by using body rotation is revisited in an adjoint-based optimal control framework.
Colonius, Tim, Flinois, Thibault L. B.
core +3 more sources
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Animals, 2019 Extended-spectrum β-lactamase Enterobacteriaceae (ESBL-E) have been investigated in adult horses, but not in foals. We aimed to determine shedding and infection in neonatal foals and mares.
Anat Shnaiderman-Torban +7 more
doaj +1 more source
Biomedicines, 2020 Although extensively investigated, cancer is still one of the most devastating and lethal diseases in the modern world. Among different types, colorectal cancer (CRC) is most prevalent and mortal, making it an important subject of research.
Jan Philipp Dobert +5 more
doaj +1 more source
Heterogeneity in transmissibility and shedding SARS-CoV-2 via droplets and aerosols
medRxiv, 2020 A growing number of studies provide insight into how SARS-CoV-2 spreads1-7. Yet, many factors that characterize its transmissibility remain unclear, including mechanistic correlates of overdispersion, viral kinetics, the extent to which respiratory ...
Paul Z. Chen +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Shedding of porcine circovirus type 1 DNA and rotavirus RNA by infants vaccinated with Rotarix®
Human Vaccines & Immunotherapeutics, 2017 Thirty-three infants aged ∼2 months had serial stool samples collected after receipt of Rotarix® vaccine dose 1, and were assessed for shedding of porcine circovirus type 1 DNA and Rotavirus group A RNA by molecular methods.
Slavica Mijatovic-Rustempasic +8 more
doaj +1 more source
Experimental Inoculation of Egyptian Fruit Bats (Rousettus aegyptiacus) with Ebola Virus
Viruses, 2016 Colonized Egyptian fruit bats (Rousettus aegyptiacus), originating in South Africa, were inoculated subcutaneously with Ebola virus (EBOV). No overt signs of morbidity, mortality, or gross lesions were noted.
Janusz T. Paweska +5 more
doaj +1 more source
CMB photons shedding light on dark matter
, 2012 The annihilation or decay of Dark Matter (DM) particles could affect the thermal history of the universe and leave an observable signature in Cosmic Microwave Background (CMB) anisotropies.
+26 more
core +3 more sources