Results 41 to 50 of about 1,162,244 (382)
ACE2 Shedding and the Role in COVID-19
Frontiers in Cellular and Infection Microbiology, 2022 Angiotensin converting enzyme 2 (ACE2), a transmembrane glycoprotein, is an important part of the renin-angiotensin system (RAS). In the COVID-19 epidemic, it was found to be the receptor of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2 ...
Jieqiong Wang, Hui-ying Zhao, Y. An
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A mathematical model of ctDNA shedding predicts tumor detection size
Science Advances, 2020 A mathematical model of tumor evolution and ctDNA shedding informs new cancer early detection approaches. Early cancer detection aims to find tumors before they progress to an incurable stage.
S. Avanzini +7 more
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VaccinesBackground: Vaccination is often a highly effective approach for protecting against clinical disease and mortality caused by viruses. However, vaccine efficacy against viral transmission has rarely been assessed, which can provide vital information on ...
Juliette Doumayrou +3 more
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Frontiers in Immunology, 2019 Efficient clearance of transformed cells by Natural Killer (NK) cells is regulated by several activating receptors, including NKG2D, NCRs, and DNAM-1.
Rosa Molfetta +3 more
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Shedding light on GPIbα shedding
Current Opinion in HematologyPurpose of review Ectodomain shedding has been investigated since the late 1980s. The abundant and platelet specific GPIbα receptor is cleaved by ADAM17 resulting in the release of its ectodomain called glycocalicin. This review will address the role of glycocalicin as an end-stage marker of platelet turnover and storage lesion
Debaene, Caitlin +2 more
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Pathogenicity and Viral Shedding of MERS-CoV in Immunocompromised Rhesus Macaques
Frontiers in Immunology, 2018 Middle East respiratory syndrome coronavirus (MERS-CoV) has recently emerged in the Middle East. Since 2012, there have been approximately 2,100 confirmed cases, with a 35% case fatality rate. Disease severity has been linked to patient health status, as
Joseph Prescott +8 more
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Frontiers in Oncology, 2022 Cervical cancer ranks fourth among the most commonly diagnosed malignant tumors in women worldwide. Previously published evidence suggested a possible connection between the expression of the membrane-bound heparan sulfate proteoglycan syndecan-1 (Sdc-1)
Katharina Hilgers +6 more
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Shedding of APP limits its synaptogenic activity and cell adhesion properties
Frontiers in Cellular Neuroscience, 2014 The Amyloid precursor protein (APP) plays a central role in Alzheimer’s disease (AD) and has essential synapse promoting functions. Synaptogenic activity as well as cell adhesion properties of APP presumably depend on trans-cellular dimerization via its ...
Ronny eStahl +9 more
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Modeling the catarrhal stage of Bordetella pertussis upper respiratory tract infections in mice
Disease Models & Mechanisms, 2022 Pertussis (whooping cough) is a highly transmissible human respiratory disease caused by Bordetella pertussis, a human-restricted pathogen. Animal models generally involve pneumonic infections induced by depositing large numbers of bacteria in the lungs ...
Illiassou H. Soumana +10 more
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Optimal under voltage load shedding based on stability index by using artificial neural network [PDF]
, 2020 Power system is exceptionally sensitive at the generation and consumer side. Inconsistent power requirement under general power production environment may cause power system to approach breakdown or power outages.
Sharman, Sundarajoo
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