Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Salmonella Infection Level in Danish Indoor and Outdoor Pig Production Systems measured by Antbodies in Meat Juice and Faecal Shedding on-farm and at Slaughter [PDF]
The prevalence of Salmonella shedding was compared in 34 organic, conventional outdoor, and indoor pig herds. Individual faecal and meat juice samples from 30-50 pigs per herd were analysed for presence of Salmonella, and Salmonella antibodies ...
Bonde, M., Sørensen, J.T.
core
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Pilot Study: Long-Term Shedding of SARS-CoV-2 in Urine: A Threat for Dispersal in Wastewater
Only 4 months after the beginning of SARS-CoV-2 epidemic, the world is facing a global pandemic due to a complex and insidious virus that today constantly poses new challenges.
Andreina Baj +8 more
doaj +1 more source
Effects of cyclic adenosine 3,5-monophosphate on photoreceptor disc shedding and retinomotor movement. Inhibition of rod shedding and stimulation of cone elongation. [PDF]
As a test of the hypothesis that cyclic nucleotides play a role in the regulation of retinomotor movements and disc shedding in the photoreceptor-pigment epithelial complex, we have used an in vitro eyecup preparation that sustains both disc shedding and
Besharse, J, BURNSIDE, Beth, Dunis, D
core +1 more source
Supernovae Shedding Light on Gamma-Ray Bursts [PDF]
We review the observational status of the Supernova (SN)/Gamma-Ray Burst (GRB) connection. In section 2 we provide a short summary of the observational properties of core-collapse SNe. In sections 3-6 we review the circumstantial evidences and the direct
Della Valle, M.
core +3 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Effect of pig production system and transport on the potential pathogen transfer risk into the food chain from Salmonella shed in pig faeces [PDF]
The prevalence of faecal Salmonella shedding has been compared in organic, conventional outdoor, and indoor finishing pig herds in a Danish survey with participation of 34 herds. Individual faecal and meat juice samples were collected from 30-50 pigs per
Bonde, Marianne, Sørensen, Jan Tind
core
Investigation of a drag reduction on a circular cylinder in rotary oscillation [PDF]
Drag reduction in two-dimensional flow over a circular cylinder, achieved using rotary oscillation, was investigated with computational simulations. In the experiments of Tokumaru & Dimotakis (1991), this mechanism was observed to yield up to 80% drag ...
Leonard, A., Shiels, D.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source

