Results 81 to 90 of about 1,131,795 (383)

Persistent viral shedding of SARS‐CoV‐2 in faeces – a rapid review

open access: yesmedRxiv, 2020
In addition to respiratory symptoms, COVID‐19 can present with gastrointestinal complaints suggesting possible faeco‐oral transmission. The primary aim of this review was to establish the incidence and timing of positive faecal samples for SARS‐CoV‐2 in ...
Sunnia Gupta   +4 more
semanticscholar   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Multi criteria decision making on load shedding scheme in an islanded system [PDF]

open access: yes, 2013
Any interruptions to the electrical system can cause loss of the power supply due to the burden of the generator. In industries, intenuption in power system can cause million of losses when the shortage of supply occurs.
Jakuil, Alester G
core  

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Fenologia de Paratecoma peroba (Bignoniaceae) em uma floresta estacional semidecidual do norte fluminense, Brasil

open access: yesRodriguésia
Resumo Estudos fenológicos auxiliam na compreensão do comportamento das espécies em resposta a alterações no ambiente e são também importantes para a conservação e manejo das mesmas. A fenologia de Paratecoma peroba (Record & Mell) Kuhlm. foi estudada no
Beatriz Lacerda Almeida Lins   +1 more
doaj   +1 more source

Proteolysis of Gingival Keratinocyte Cell Surface Proteins by Gingipains Secreted From Porphyromonas gingivalis – Proteomic Insights Into Mechanisms Behind Tissue Damage in the Diseased Gingiva

open access: yesFrontiers in Microbiology, 2020
Porphyromonas gingivalis, the main etiologic agent of periodontitis, secretes cysteine proteases named gingipains. HRgpA and RgpB gingipains have Arg-specificity, while Kgp gingipain is Lys-specific.
Katarina Hočevar   +11 more
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Oncolytic Viruses: An Inventory of Shedding Data from Clinical Trials and Elements for the Environmental Risk Assessment

open access: yesVaccines, 2023
Attenuated and/or genetically modified oncolytic viruses (OV) gain increasing interest as a promising approach for cancer therapy. Beside the assessment of subject safety, quality and efficacy aspects of medicinal products for human use, genetically ...
Sheela Onnockx   +2 more
doaj   +1 more source

Stability and collapse of rapidly rotating, supramassive neutron stars: 3D simulations in general relativity [PDF]

open access: yes, 1999
We perform 3D numerical simulations in full general relativity to study the stability of rapidly rotating, supramassive neutron stars at the mass-shedding limit to dynamical collapse. We adopt an adiabatic equation of state with $\Gamma = 2$ and focus on
A. M. Abrahams   +40 more
core   +2 more sources

Shedding Light on the Shadow Economy: A Global Database and the Interaction with the Official One

open access: yesSocial Science Research Network, 2019
Using the multiple indicator-multiple cause (MIMIC) approach, this paper generates a novel global database by estimating the size of the shadow economy for 157 countries over 1991 to 2017. The results suggest that the OECD countries are by far the lowest
Leandro Medina, F. Schneider
semanticscholar   +1 more source

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