Results 51 to 60 of about 730,516 (311)

Research on theoretical calculation model of shield segments floating amount and floating control measures

open access: yes矿业科学学报, 2021
The floating of the shield segment will cause the segment to be misaligned and damaged, reducing the overall structural strength, waterproof performance and service life of the tunnel.
Yang Zhiyong   +5 more
doaj   +1 more source

U–Pb dating and Sm–Nd isotopic analysis of granitic rocks from the Tiris Complex : new constaints on key events in the evolution of the Reguibat Shield, Mauritania [PDF]

open access: yes, 2012
The Reguibat Shield of N Mauritania and W Algeria represents the northern exposure of the West African Craton. As with its counterpart in equatorial West Africa, the Leo Shield, it comprises a western Archaean Domain and an eastern Palaeoproterozoic ...
Abdouloye, T.B.   +6 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Heat shield oven [PDF]

open access: yes, 1969
Oven for heat treating heat ...
Beckerle, L. D.
core   +1 more source

Systematic study of effect of cross-drafts and nozzle diameter on shield gas coverage [PDF]

open access: yes, 2013
A shield gas flow rate of 15–20 L min21 is typically specified in metal inert gas welding, but is often adjusted to as high as 36 L min21 by welders in practice. Not only is this overuse of shield gas wasteful, but uncontrolled high gas flows can lead to
Beyer, V.   +5 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Lithosphere-asthenosphere system in shield areas of North America and Europe

open access: yesAnnals of Geophysics, 1997
In previous papers surface dispersion data have been combined with the results of deep seismic refraction data to derive a regionalization of the lithosphere-asthenosphere system and to investigate the presence of significant heterogeneity down to depths
P. Pierri, V. Del Gaudio, G. Calcagnile
doaj   +1 more source

Radioprotection for Astronauts’ Missions: Numerical Results on the Nomex Shielding Effectiveness

open access: yesLife, 2023
Space missions with humans expose the crews to ionizing radiation, mainly due to the galactic cosmic radiation (GCR). All radiation protection programs in space aim to minimize crews’ exposure to radiation.
Filomena Loffredo   +4 more
doaj   +1 more source

Spherical shield Patent [PDF]

open access: yes, 1965
Flexible bellows joint shielding sleeve for propellant transfer ...
Noreen, S. J., Pfleger, R. O.
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy