Results 41 to 50 of about 312,777 (262)

Analisis Shift-share Arcelus Propinsi Kalimantan Tengah

open access: yesJurnal Ekonomi & Studi Pembangunan, 2010
Beberapa kesimpulan dan implikasi kebijakan yang dapat diambil seteiah dilakukan analisis spesialisasi regional terhadap Propinsi Kalimantan Tengah.
hermanto hermanto
doaj  

Análise da dinâmica e especialização das atividades criativas nas capitais brasileiras e cidades criativas da Unesco

open access: yesDiálogo com a Economia Criativa, 2023
Este artigo tem por objetivo discutir o crescimento das atividades criativas, que fazem interface com o turismo, nas 27 capitais brasileiras e nas cidades criativas reconhecidas pela Organização das Nações Unidas para a Educação, a Ciência e a Cultura ...
Jonas da Silva Henrique
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Dinâmica das exportações no estado de Minas Gerais: uma análise de shift-share (2006-2016)

open access: yesGeosul, 2021
O presente trabalho teve como objetivo analisar as exportações das mesorregiões de Minas Gerais entre os anos 2006 e 2016, no qual realizou-se um comparativo entre os resultados das mesorregiões e os do Estado como um todo.
Rosa Livia Gonçalves Montenegro   +1 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

RESILIÊNCIA ECONÔMICA E DINÂMICA REGIONAL-SETORIAL NO BRASIL PÓS-CRISE/REGIONAL RESILIENCE AND SECTOR DINAMICS IN POST-CRISIS BRAZIL: AN EXPLORATORY ANALYSIS FOR THE 2014-2019 PERIOD

open access: yesInforme Gepec, 2022
Essa pesquisa busca explorar a resiliência economia regional brasileira para analisar como a crise de 2015-16 impactou sua base econômica. Dessa forma, podemos identificar quais estruturas produtivas conseguem proteger a região de uma crise. Para tanto,
Paulo Henrique de Cezaro Eberhardt   +1 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Local multiplier of industrial employment: Brazilian mesoregions (2000-2010)

open access: yesBrazilian Journal of Political Economy
This paper estimates the local multiplier of manufacturing for Brazil (2000-2010). The method is based on (Moretti, 2010) and on (Moretti and Thulin, 2012), who estimated these multipliers for the U.S. and Sweden.
GUILHERME MACEDO, LEONARDO MONASTERIO
doaj   +1 more source

Employment Local Multipliers in Mexico

open access: yesSobre México, 2021
In this paper we estimate the local multiplier of employment in the tradable sector on employment in the non-tradable sector in Mexico, over the 2000-2010 period.
Nataly Hernández, Irvin Rojas
doaj  

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