Results 101 to 110 of about 293,216 (302)
, 1999 過疎地域の振興は21世紀を目前に控えた今日においても依然として重要な課題である。高度成長期に起源を持つこの課題を解決するために数次に渡る過疎対策が実施されてきたわけであるが、これがどのような成果を挙げてきたのか、また、今後あるべき過疎対策とは何か、我々はまだはっきりした答えを持っていない。過疎対策の在り方を論じる上で、過疎が発生するメカニズムを明らかにすることは2つの意味で重要と考えられる。第一に、対症療法に過ぎない過疎対策からの脱却を図る手段を提供すること、第二に ...
1932 +9 more
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Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Employment shifts in the Leisure and Hospitality sector along the Gulf coast following Hurricane Katrina were explored using spatial shift-share analysis.
Evans, Garen K.
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Income Disparities and Trends in Manufactured Exports Across the States and Territories of Australia: 1989/90 - 2000/01 [PDF]
This paper documents differences in the levels and growth rates of manufactured exports across the Australian states and territories over the period 1989/90 - 2000/01 and then re-interprets these differences using shift-share analysis.
Jayanthakumaran, Kankesu, Neri, Frank
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Regional Development Policies And Industrial Employment Change In Turkey: A Shift Share Analysis (1992-2008) [PDF]
, 2012 It is necessary for policy-makers to assess region's overall performance and given sector's efficiency relative to other industry sector's performance in the region to achieve regional policy objectives.
Elburz, Zeynep, Gezici, Ferhan
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Employment growth in Ceara: a shift-share analysis (2000-2005)
Between 2000 and 2005, formal employment grew by 33.15% in Ceara (Brazil). Hence, the main objective of this paper was to analyze which municipalities and sectors contributed the most to such growth through a shift-share analysis of employment.
Gondim Nogueira, Cláudio André +1 more
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Shift-share analysis revisited: the allocation effect and the stability of regional structure
, 1977 This paper examines the Esteban-Marquillas reformulation of the ''classical'' shift-share equation. The revised equation is used to decompose sectoral employment growth between 1960 and 1970 into four effects that measure differential
Olsen, R. J., Herzog, Jr., H. W.
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