Results 111 to 120 of about 4,902,382 (344)

Optimal Management with Potential Regime Shifts [PDF]

open access: yes
We analyze how the threat of a potential future regime shift affects optimal management. We use a simple general growth model to analyze four cases that involve combinations of stock collapse versus changes in system dynamics, and exogenous versus ...
De Zeeuw, A.   +2 more
core  

Control Over Work Hours and Alternative Work Schedules [PDF]

open access: yes, 2001
[Excerpt] Alternative work schedules encompass work hours that do not necessarily fall inside the perimeters of the traditional and often rigid 8-hour workday or 40-hour workweek.
AFL-CIO Working Women’s Department   +1 more
core   +1 more source

Trabalhadoras de turno noturno: relações de gênero, produção de vulnerabilidades e promoção da saúde

open access: yesRevista Brasileira de Saúde Ocupacional
Objetivo analisar os impactos que o trabalho noturno exerce sobre a saúde de trabalhadoras do setor metal-mecânico.
Juliana Figueiredo Arreal   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Shift Work and Shift Work Sleep Disorder [PDF]

open access: yesChest, 2017
Emerson M. Wickwire   +3 more
openaire   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Data driven rank tests for classes of tail alternatives [PDF]

open access: yes, 1999
Tail alternatives describe the frequent occurrence of a non-constant shift in the two-sample problem with a shift function increasing in the tail. The classes of shift functions can be built up using Legendre polynomials.
Albers, W.   +2 more
core   +2 more sources

Scheduling of night shift work

open access: yesSafety and Health at Work, 2022
Anne Helene Garde
doaj   +1 more source

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