Results 181 to 190 of about 4,956,823 (296)

Association Between Shift Work and Auditory-Cognitive Processing in Middle-Aged Healthcare Workers. [PDF]

Audiol Res
Roque M, Marques T, Serrano M.
europepmc   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Night shift work and dietary behaviors: a comparative analysis of European night shift and day workers from the SHIFT2HEALTH online survey. [PDF]

Nutr J
Klink U, Feskens EJM, Lucassen DA, Vingerhoeds MH, Haider S, Papantoniou K, Matullat I, Cuparencu C, Aufschnaiter AL, Fuchs-Neuhold B, Höfler C, Wallner M, Binder-Olibrowska KW, Wrzesińska MA, Lammers-van der Holst HM, Santonja I, Scionti K, Schoissengeier V, Wagner KH, Wakolbinger M, Winzer E, Ummels M, Jilani H, SHIFT2HEALTH consortium.   +23 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Characterising the impact of shift work on diet and glucose variability in healthcare employees living with type 2 diabetes: The Shift-Diabetes study. [PDF]

Diabet Med
Gibson R, D'Annibale M, Palla L, Tejo F, McGowan B, Vetter C, Lorencatto F, Oliver N, Guess N.   +8 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Night-shift work and its association with metabolic syndrome. [PDF]

Medicine (Baltimore)
Lin SC, Yeh WC, Liu ZX, Hsu HF, Chen JY.
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Association of shift work with metabolic dysfunction-associated fatty liver disease among subway workers. [PDF]

Front Public Health
Peng R, Shi B, Liu J, He Z.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source