Results 201 to 210 of about 4,902,382 (344)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The impact of shift work on paramedics and their practice: Protocol for a simulated paramedic shift work study. [PDF]

PLoS One
Hirello LM, Drummond SPA, Bowles KA, Wolkow AP.   +3 more
europepmc   +1 more source

Physical activity, sedentary time and sleep and associations with mood states, shift work disorder and absenteeism among nurses: an analysis of the cross-sectional Champlain Nurses’ Study

, 2020
Sonia Hajo, Jennifer L. Reed, Harleen Hans, Heather Tulloch, Robert D. Reid, Stéphanie A. Prince   +5 more
openalex   +1 more source

Generational Career Shifts: How Matures, Boomers, Gen Xers, and Millennials View Work [PDF]

, 2018
Eddy S. Ng, Seán Lyons, Linda Schweitzer   +2 more
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Rotating Shift Work and Burnout Among Nurses in Hebron Hospitals, West Bank, Palestine: A Cross-Sectional Study. [PDF]

Public Health Chall
Jaradat Y, Qtait M, Alqaissi N, Omer DA, Atawneh A, Sharkh AA, Baradia M, Drabee HA.   +7 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Night-shift work and its association with metabolic syndrome. [PDF]

Medicine (Baltimore)
Lin SC, Yeh WC, Liu ZX, Hsu HF, Chen JY.
europepmc   +1 more source

Shifting agrarian labour regimes, ecology, and the crisis for Dalit women’s work in India [PDF]

Shreya Sinha
openalex   +1 more source

Life Quality: The Night Shift Work Challenge To Nursing Team / Qualidade de Vida: O Desafio do Trabalho Noturno Para a Equipe de Enfermagem [PDF]

, 2018
Alexia Gonçalves Sena, Mirela Lopes de Figueiredo, Écila Campos Mota, Fernanda Marques da Costa, Patrícia Fernandes do Prado, Cássio de Almeida Lima   +5 more
openalex   +1 more source