Results 61 to 70 of about 1,432,960 (308)

Night shift work characteristics and occupational co-exposures in industrial plants in Łódź, Poland [PDF]

, 2013
Objectives: Night shift work involving circadian rhythm disruption has been classified by IARC as a probably carcinogenic to humans (Group 2A). Little is known about co-exposures of the night shift work in occupational settings.
Konieczko, Katarzyna, Beata Pepłońska, Burdelak, Weronika, Weronika Burdelak, Katarzyna Konieczko, Pepłońska, Beata, Agnieszka Bukowska, Bukowska, Agnieszka, Krysicka, Jolanta, Jolanta Krysicka   +9 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Investigating the Circadian Rhythm Type and its Relation to the Problems Caused by Shift work: a Case Study-Workers in one of Iran’s Iron-Ore Mines

International Journal of Occupational Hygiene, 2019
Nowadays, shift work systems are a very common work schedule in developed and industrialized societies. The human body needs to adapt itself to different cycles of sleep and awakening. These will predispose persons to various physical, psychological, and
Mahdiyeh Shafiezadeh Bafghi, Mojtaba Moghaddasi, Vida Sadat Anoosheh, Fatemeh Aminaei, Reza Jafari Nodoushan   +4 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Rest breaks – a countermeasure for work-related injuries?

Scandinavian Journal of Work, Environment & Health, 2014
The main idea behind supplementary rest breaks within a work shift is to promote recovery from work, a process known to be important for health in the long-run (1). Supplementary rest breaks are also used to promote occupational safety.
Mikael Sallinen
doaj   +1 more source

Investigating the Correlation between Shift Work and Job Commitment and the Mediating Role of Work-Life Balance among Emergency Medical Personnel [PDF]

Journal of Social Behavior and Community Health, 2023
Background: Shift work is a job stressor. Health service is one of the centers where shift work is an integral part, and the level of job commitment in staff has a significant impact on service delivery.
Monika Motaghi, Lida Gholizade, Mehdi Eslami   +2 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Shift work, sleep, and sleepiness - differences between shift schedules and systems

Scandinavian Journal of Work, Environment & Health, 2010
In this narrative review, we examined what level of research evidence is available that shift workers’ sleep–wake disturbances can be minimized through ergonomic shift scheduling.
Mikael Sallinen, Göran Kecklund
doaj   +1 more source

Night-shift work duration and breast cancer risk: an updated systematic review and meta-analysis

BMC Women's Health, 2021
Background The International Agency for Research on Cancer (IARC) has classified shift work as a possible human carcinogen. The results of systematic on this topic is contradictory. This systematic review and meta-analysis, therefore, aimed to update the
E. Manouchehri, A. Taghipour, V. Ghavami, A. Ebadi, F. Homaei, R. Latifnejad Roudsari   +5 more
doaj   +1 more source