Results 71 to 80 of about 1,311,791 (261)

The association between shift work, shift work sleep disorders and premature ejaculation in male workers

BMC Public Health
Objective Shift work and Shift Work Sleep Disorder (SWSD) are known to affect the secretion of several neurotransmitters and hormones associated with premature ejaculation (PE).
Zhenming Zheng, Jiashan Pan, Zhimin Chen, Pan Gao, Jingjing Gao, Hui Jiang, Xiansheng Zhang   +6 more
doaj   +1 more source

A Survey of Shift Work and Work Ability Index among Nurses: A Case Study in Educational Hospital, Ahvaz, Iran

International Journal of Occupational Hygiene, 2021
Shift work is a social phenomenon with adverse effects on the lives and health of people in various aspects. This adverse effect decreases shift workers’ ability over a time period.
Leila Ibrahimi Ghavamabadi, Behzad Fouladi Dehaghi, Behnoush Jafari   +2 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Comparison the frequency of symptoms of acute shift work maladaption syndrome between two groups of shift workers

Salāmat-i kār-i Īrān, 2013
Background and aims: Shift work intolerance has symptoms that names shift work maladaption syndrome. The aim of this study is the comparison between frequency of symptoms of acute shift work maladaption syndrome in two groups of shift workers.   Methods:
Seyedeh Negar Assadi
doaj  

Working hour characteristics and schedules among nurses in three Nordic countries – a comparative study using payroll data

BMC Nursing, 2019
Background Organisation of working hour schedules in the Northern European countries are rather similar. EU countries are obliged to adopt national legislation regarding duration of weekly working hours and rest periods. Yet, working hour characteristics
Anne Helene Garde, Anette Harris, Øystein Vedaa, Bjørn Bjorvatn, Johnni Hansen, Åse Marie Hansen, Henrik A. Kolstad, Aki Koskinen, Ståle Pallesen, Annina Ropponen, Mikko I. Härmä   +10 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Trabalhadoras de turno noturno: relações de gênero, produção de vulnerabilidades e promoção da saúde

Revista Brasileira de Saúde Ocupacional
Objetivo analisar os impactos que o trabalho noturno exerce sobre a saúde de trabalhadoras do setor metal-mecânico.
Juliana Figueiredo Arreal, Laura Cecilia López   +1 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source