Results 31 to 40 of about 172,904 (241)

Shift work, clinically significant sleep disorders and mental health in a representative, cross-sectional sample of young working adults

Scientific Reports, 2022
Mental health conditions confer considerable global disease burden in young adults, who are also the highest demographic to work shifts, and of whom 20% meet criteria for a sleep disorder.
Amy C. Reynolds, Bastien Lechat, Yohannes Adama Melaku, Kelly Sansom, Brandon W. J. Brown, Meagan E. Crowther, Sian Wanstall, Kathleen J. Maddison, Jennifer H. Walsh, Leon Straker, Robert J. T. Adams, Nigel McArdle, Peter R. Eastwood   +12 more
doaj   +1 more source

Identifying Risk and Protective Factors for Shift Work Sleep Disorder: Insights from UK Biobank Night Shift Workers

Clocks & Sleep
Shift Work Sleep Disorder (SWSD) is a significant and highly prevalent condition affecting up to 48% of individuals with irregular work schedules. The diagnostic criteria for SWSD include persistent insomnia or sleepiness in relation to shift work, not ...
Jürgen Degenfellner, Susanne Strohmaier, Magdalena Zebrowska, Ingvild Saksvik-Lehouillier, Eva Schernhammer   +4 more
doaj   +1 more source

Shift Work Sleep Disorder and Night Shift Work Significantly Impair Erectile Function

The Journal of Sexual Medicine, 2020
Abstract Objectives Here we examine the association between shift work sleep disorder (SWSD) and erectile dysfunction (ED) in shift workers. Methods Men presenting to a single andrology clinic between January 2014 and July 2017 ...
Rodriguez, Katherine M, Kohn, Taylor P, Kohn, Jaden R, Sigalos, John T, Kirby, E Will, Pickett, Stephen M, Pastuszak, Alexander W, Lipshultz, Larry I   +7 more
openaire   +5 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Bright environmental light improves the sleepiness of nightshift ICU nurses

Critical Care, 2018
Background Shift work can disturb circadian homeostasis and result in fatigue, excessive sleepiness, and reduced quality of life. Light therapy has been shown to impart positive effects in night shift workers.
John E. Griepentrog, Hanna E. Labiner, Scott R. Gunn, Matthew R. Rosengart   +3 more
doaj   +1 more source

Insomnia, excessive sleepiness, excessive fatigue, anxiety, depression and shift work disorder in nurses having less than 11 hours in-between shifts. [PDF]

PLoS ONE, 2013
STUDY OBJECTIVE: To assess if less than 11 hours off work between work shifts (quick returns) was related to insomnia, sleepiness, fatigue, anxiety, depression and shift work disorder among nurses.
Maria Fagerbakke Eldevik, Elisabeth Flo, Bente Elisabeth Moen, Ståle Pallesen, Bjørn Bjorvatn   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Psychometric of the Persian Version of Shift Work Disorder Questionnaire in Employee Women [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023
Introduction: Shift work disorder (SWD) is a sleep disorder that affects the circadian rhythm and is characterized by symptoms such as excessive daytime sleepiness and insomnia. This condition can significantly increase the risk of accidents and diminish
Ashraf Moini, Farideh Malekzadeh, Behnaz Navid, Maryam Mohammadi, Reza Omani-Samani   +4 more
doaj  

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source