Results 71 to 80 of about 655,319 (266)

Inhomogeneous Pairing in Highly Disordered s-wave Superconductors

, 2000
We study a simple model of a two-dimensional s-wave superconductor in the presence of a random potential in the regime of large disorder. We first use the Bogoliubov-de Gennes (BdG) approach to show that, with increasing disorder the pairing amplitude ...
Ghosal, Amit, Randeria, Mohit, Trivedi, Nandini   +2 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Influence of anti-site disorder and electron-electron correlations on the electronic structure of CeMnNi$_4$

, 2018
CeMnNi$_4$ exhibits an unusually large spin polarization, but its origin has baffled researchers for more than a decade. We use bulk sensitive hard x-ray photoelectron spectroscopy (HAXPES) and density functional theory based on the Green's function ...
Barman, Sudipta Roy, Chainani, Ashish, Chakrabarti, Aparna, D'Souza, Sunil Wilfred, Dhaka, Rajendra Singh, Dhar, Sudesh Kumar, Gloskovskii, Andrei, Raychaudhuri, Pratap, Sadhukhan, Pampa, Singh, Vipin Kumar   +9 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Disorder-Induced First Order Transition and Curie Temperature Lowering in Ferromagnatic Manganites

, 2006
We study the effect that size disorder in the cations surrounding manganese ions has on the magnetic properties of manganites. This disorder is mimic with a proper distribution of spatially disordered Manganese energies.
B. Dabrowski, C. Zener, E. Dagotto, G. D. Mahan, J. Salafranca, L. Brey, L. M. Rodríguez-Martínez   +6 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Interplay between disorder and intersubband collective excitations in the two-dimensional electron gas

, 2001
Intersubband absorption in modulation-doped quantum wells is usually appropriately described as a collective excitation of the confined two-dimensional electron gas.
Beltram, Fabio, Luin, Stefano, Marcadet, Xavier, Pellegrini, Vittorio, Sirtori, Carlo   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Shift work and autoimmune thyroid disorders.

International journal of immunopathology and pharmacology, 2006
Stress induces autoimmune disorders by affecting the immune response modulation. Recent studies have shown that shift work stress may enhance the onset of the autoimmune Graves hyperthyroidism. On the other hand, the possible association between occupational stress and autoimmune hypothyroidism has not yet been investigated.
MAGRINI, ANDREA, PIETROIUSTI, ANTONIO, Coppeta, L, Babbucci, A, Barnaba, E, Papadia, C, Iannaccone, U, Boscolo, P, Bergamaschi, E, Bergamaschi, A.   +9 more
openaire   +4 more sources