Results 71 to 80 of about 15,095,322 (254)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Schizophrenia and Bipolar Disorder in Urban Areas [PDF]

open access: yes, 2007
Background Earlier studies have shown that schizophrenic patients are more likely to be living in densely populated inner city areas, whereas bipolar patients are more widely distributed.
Cooke, Angela   +5 more
core   +2 more sources

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Periodic self-rostering in shift work : correspondence between objective work hours, work hour preferences (personal fit), and work schedule satisfaction

open access: yes, 2012
Objectives The main objective of the present study was to investigate relative personal fit as the association between rated needs and preferences for work hours, on the one hand, and actual work hours, on the other hand, in three groups (hospital, call ...
Kecklund, G,   +6 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Shift work and autoimmune thyroid disorders.

open access: yesInternational journal of immunopathology and pharmacology, 2006
Stress induces autoimmune disorders by affecting the immune response modulation. Recent studies have shown that shift work stress may enhance the onset of the autoimmune Graves hyperthyroidism. On the other hand, the possible association between occupational stress and autoimmune hypothyroidism has not yet been investigated.
MAGRINI, ANDREA   +9 more
openaire   +5 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

HUBUNGAN GANGGUAN TIDUR DENGAN KELELAHAN PADA SISTEM KERJA BERGILIR (SHIFT) MALAM TERHADAP KARYAWAN MINIMARKET 24 JAM DI KOTA DENPASAR

open access: yesJurnal Ergonomi Indonesia, 2015
In this globalization era, all people are required to work, on other side, demand for services also increased so that some companies use a shift work and divided the shift into morning shift and night shift to improve services.
I.G.A. NADYA WULANDARI   +1 more
doaj  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Shift work sleep disorder in nurses: a concept analysis

open access: yesBMC Nursing
Aim This study seeks to elucidate the concept of shift work sleep disorder (SWSD) among nurses, thereby offering a comprehensive understanding that can inform future research and practical interventions. Methods Walker and Avant’s concept analysis method
Liangmeng Yu   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy