Results 61 to 70 of about 15,095,322 (254)

Unadjusted odds ratio (OR) and confidence intervals (CI) for variables associated with shift work disorder and severe shift work disorder.

, 2013
Unadjusted odds ratio (OR) and confidence intervals (CI) for variables associated with shift work disorder and severe shift work disorder.
Lee Di Milia (286749), Siri Waage (286752), Ståle Pallesen (35253), Bjørn Bjorvatn (35254)   +3 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Shift work sleep disorders and associated factors among nurses at federal government hospitals in Ethiopia: a cross-sectional study

BMJ Open, 2019
Objective The current study was conducted to assess the prevalence and associated factors of shift work sleep disorder among nurses working at Ethiopian federal government hospitals in Addis Ababa.Methods An institutional-based, cross-sectional study was
Sintayehu Asnakew, Kalkidan Kassa Haile, Tsegereda Waja, Habtamu Bogale Kerbih   +3 more
doaj   +1 more source

Insomnia, excessive sleepiness, excessive fatigue, anxiety, depression and shift work disorder in nurses having less than 11 hours in-between shifts. [PDF]

PLoS ONE, 2013
STUDY OBJECTIVE: To assess if less than 11 hours off work between work shifts (quick returns) was related to insomnia, sleepiness, fatigue, anxiety, depression and shift work disorder among nurses.
Maria Fagerbakke Eldevik, Elisabeth Flo, Bente Elisabeth Moen, Ståle Pallesen, Bjørn Bjorvatn   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The prevalence of Shift Work Sleep Disorder and The Quality Of Sleep Among Nurses Working in Selected Hospitals, Hyderabad

Indian Journal of Psychiatric Nursing, 2018
Now a days the shift work is one of the most important cause for sleeping disorders among nurses. In almost every occupation round the clock performance is expected and the census data shows that there is a large segment of the work force is employed on ...
Anumol Joseph, Sister Mary Brooke, Jelby, Pushpalatha, Sharon, Sunitha   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The Association Between Shift Work and Immunological Biomarkers in Nurses

Frontiers in Public Health, 2020
Objectives: Shift work is associated with several negative health effects. The underlying pathophysiological mechanisms are unclear, but low-grade inflammation has been suggested to play a role.
Bjørn Bjorvatn, Bjørn Bjorvatn, John Axelsson, John Axelsson, Ståle Pallesen, Ståle Pallesen, Siri Waage, Siri Waage, Øystein Vedaa, Øystein Vedaa, Kjersti M. Blytt, Kjersti M. Blytt, Hogne V. Buchvold, Bente E. Moen, Eirunn Thun   +14 more
doaj   +1 more source