Results 81 to 90 of about 4,742,454 (347)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The assessment of executive function abilities in healthy and neurodegenerative aging—A selective literature review

open access: yesFrontiers in Aging Neuroscience
Numerous studies have examined executive function (EF) abilities in cognitively healthy older adults and those living with mild cognitive impairment (MCI) and Alzheimer's disease (AD).
Mojitola I. Idowu   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

L’objet dans les nécropoles mégariennes : réflexion méthodologique autour de la notion de « dépôt funéraire »

open access: yesPallas, 2014
By examining the types and position of artefacts in a grave at its opening, an archaeologist can get many information on the part each object played in the funeral, the symbolic value attached to them and the course of the funeral itself.
Reine-Marie Berard
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Performance Indicators Definition during Hydromechanical Transmission Gear Shift

open access: yesМеханика машин, механизмов и материалов, 2011
The microprocessor controller deviсе and mathematical model for control were presented. The performance indicators of mobile machines hydro mechanical transmission are shown to determine during shift road testing or modeling experimental period.
V.N. Basalaev   +4 more
doaj  

Changes in basic meanings from Proto-Austronesian to Acehnese

open access: yesStudies in English Language and Education, 2018
Changes in meaning or semantic changes are the area of diachronic linguistics. The Acehnese language is a derivative of the Proto-Austronesian (PAN) language that has had changes in the meaning of its lexicon that have become the object of this ...
Dohra Fitrisia, Dwi Widayati
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Bioinformatics software, shifting to mobility [PDF]

open access: yes, 2014
Presentación en Escuela de Verano del trabajo en desarrollo para el proyecto Mr.Symbiomath IAPP project (Code: 324554)Mobile devices are pervading all the work environments with such swiftness that makes past decades of computerization appear lethargic.
Falgueras-Cano, Juan
core  

Cognitive impairment in Parkinson's disease : is it a unified phenomenon? [PDF]

open access: yes, 2005
Parkinson's disease (PD) has long been associated with dementia. This has been found to correlate with participant age, age at onset of PD and severity of PD.
Brendel, Bettina   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy