Results 101 to 110 of about 624,139 (310)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Frontiers in Aging NeuroscienceNumerous studies have examined executive function (EF) abilities in cognitively healthy older adults and those living with mild cognitive impairment (MCI) and Alzheimer's disease (AD).
Mojitola I. Idowu +2 more
doaj +1 more source
Heritage diplomacy and Australia's responses to a shifting landscape of international conservation [PDF]
, 2014 The economic and political shifts that together constitute contemporary globalisation are opening up new spaces for non-Western modes of heritage governance in the international arena.
Tim Winter
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Pallas, 2014 By examining the types and position of artefacts in a grave at its opening, an archaeologist can get many information on the part each object played in the funeral, the symbolic value attached to them and the course of the funeral itself.
Reine-Marie Berard
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Changes in basic meanings from Proto-Austronesian to Acehnese
Studies in English Language and Education, 2018 Changes in meaning or semantic changes are the area of diachronic linguistics. The Acehnese language is a derivative of the Proto-Austronesian (PAN) language that has had changes in the meaning of its lexicon that have become the object of this ...
Dohra Fitrisia, Dwi Widayati
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Comparison of fluorescent down-shifting layers for increasing the efficiency of CdS/CdTe solar cells
, 2011 The poor spectral response of some Cadmium Sulfide/Cadmium Telluride (CdTe/CdS) solar cells in the UV/blue part of the spectrum can be improved through down-shifting of light using fluorescent dyes.
Markvart, Tom +4 more
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