Results 61 to 70 of about 33,059,536 (219)

Inborn errors of immunity in children with neuroinflammation

Developmental Medicine &Child Neurology, EarlyView.
Abstract Inborn errors of immunity (IEIs), an expanding group of monogenic disorders with diverse clinical manifestations, are increasingly recognized to include neuroinflammatory disease. Examples of diseases included under this umbrella are Aicardi–Goutières syndrome, deficiency of adenosine deaminase 2, familial haemophagocytic lymphohistiocytosis ...
Eppie M Yiu, Dilan Dissanayake, Jessie Cunningham, Helen Branson, Ori Scott, E Ann Yeh   +5 more
wiley   +1 more source

Use of Genomics to Investigate Historical Importation of Shiga Toxin–Producing Escherichia coli Serogroup O26 and Nontoxigenic Variants into New Zealand

Emerging Infectious Diseases, 2019
Shiga toxin–producing Escherichia coli serogroup O26 is an important public health pathogen. Phylogenetic bacterial lineages in a country can be associated with the level and timing of international imports of live cattle, the main reservoir.
A. Springer Browne, Patrick J. Biggs, David A. Wilkinson, Adrian L. Cookson, Anne C. Midwinter, Samuel J. Bloomfield, C. Reed Hranac, Lynn E. Rogers, Jonathan C. Marshall, Jackie Benschop, Helen Withers, Steve Hathaway, Tessy George, Patricia Jaros, Hamid Irshad, Yang Fong, Muriel Dufour, Naveena Karki, Taylor Winkleman, Nigel P. French   +19 more
doaj   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

An Updated Review of the Opportunities and Challenges in Insects as Food and Feed

Nutrition Bulletin, EarlyView.
ABSTRACT The global demand for sustainable protein sources is increasing in response to population growth, climate change and food insecurity. Edible insects are a promising alternative, offering nutritional, environmental and socio‐economic advantages.
Kieran David Robertson, Whitney Vale‐Hagan, Alexandros Ch. Stratakos, Olena Doran, Eleanor Drinkwater, Xian Wu, M. Elizabeth Miller, Luke Davies, Klaus W. Lange, Yukiko Nakamura, Femi Ezhuthupallickal Benny, Seirian Sumner, Anastasios Koidis, Sokratis Stergiadis, Katerina Theodoridou   +14 more
wiley   +1 more source

Hemolytic Uremic Syndrome Outbreak in Adults and Shiga Toxin–Producing Escherichia coli Negative for Locus of Enterocyte Effacement, France, 2025

Emerging Infectious Diseases
In January 2025, the Escherichia coli National Reference Center of France detected an outbreak of hemolytic uremic syndrome (HUS) in adults, caused by Shiga toxin–producing E. coli negative for locus of enterocyte effacement (LEE). The outbreak included
Justine de Larminat, Kevin La, Philippe Bidet, André Birgy, Sandrine Liguori, Pierre Phlipaux, Celine Courroux, Florence Crombé, Jorge Blanco, Paul Coppo, Antoine Dossier, Laurence Armand-Lefevre, François Xavier Weill, Carolina Silva Nodari, Gabrielle Jones, Aurelie Cointe, Stéphane Bonacorsi   +16 more
doaj   +1 more source

Comparative Pathogenicity of Wildlife and Bovine Escherichia coli O157:H7 Strains in Experimentally Inoculated Neonatal Jersey Calves

Veterinary Sciences, 2018
Shiga toxin-producing Escherichia coli, like E. coli O157:H7, are important human and animal pathogens. Naturally-acquired E. coli O157:H7 infections occur in numerous species but, particularly, cattle have been identified as a significant reservoir for ...
Elizabeth M. Antaki-Zukoski, Xunde Li, Patricia A. Pesavento, Tran H. B. Nguyen, Bruce R. Hoar, Edward R. Atwill   +5 more
doaj   +1 more source

Integrated Genotypic and Phenotypic Determinants Underpin the Environmental Persistence of Escherichia coli in Treated Sewage in Japan

Environmental Microbiology Reports, Volume 18, Issue 6, December 2026.
This study integrated genotypic and phenotypic analyses to investigate the persistence of Escherichia coli in treated sewage in Japan. Virulence‐positive isolates were dominated by phylogroups D and B1, with astA and blaTEM as the predominant virulence and resistance determinants. Among accessory siderophore genes, fecA and chuA were the most prevalent.
Ida Munfarida, Jant Cres Caigoy, Christian Xedzro, Toshi Shimamoto, Tadashi Shimamoto   +4 more
wiley   +1 more source

Fighting Fire with Fire: Phage Potential for the Treatment of E. coli O157 Infection

Antibiotics, 2018
Hemolytic⁻uremic syndrome is a life-threating disease most often associated with Shiga toxin-producing microorganisms like Escherichia coli (STEC), including E. coli O157:H7.
Cristina Howard-Varona, Dean R. Vik, Natalie E. Solonenko, Yueh-Fen Li, M. Consuelo Gazitua, Lauren Chittick, Jennifer K. Samiec, Aubrey E. Jensen, Paige Anderson, Adrian Howard-Varona, Anika A. Kinkhabwala, Stephen T. Abedon, Matthew B. Sullivan   +12 more
doaj   +1 more source

Deciphering the molecular basis of maize cold tolerance via integrative regulatory network analysis

The Plant Journal, Volume 128, Issue 3, November 2026.
SUMMARY Maize (Zea mays L.) is a globally critical but cold‐sensitive crop. Understanding the temporal organization of cold‐responsive, circadian‐associated, and hormone‐associated transcriptional programs is essential for deciphering how plants balance growth and survival under cold stress to ensure food security.
Tianshuo Li, Wei Wang, Chuang Jiang, Jinkui Cheng, Fei Yi, Liusheng Duan   +5 more
wiley   +1 more source

Multiplex PCR detection of stx1, stx2 and eaeA genes in Escherichia coli isolated from lambs in ChaharmahalvaBakhtiari, Iran

Biological Journal of Microorganism, 2013
Introduction: Pathogens can be transmitted to the humans through the consumption of contaminated meat and thus causing disease. Shiga-toxin-producing Escherichia coli can cause mild watery diarrhea to more serious complications of hemorrhagic colitis ...
Marzieh Tadi Beni, Vida Najafzadeh, Hossein Kaboli Boroujeni, Naser Khosravi, Hassan Momtaz, Hossein Tahmasby, Samaneh Mehrabiyan, Farnoush Ansari   +7 more
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