Results 131 to 140 of about 335,942 (340)

Complete genome sequences of escherichia coli phages vB_EcoM-EP75 and vB_EcoP-EP335 [PDF]

, 2019
Phages vB_EcoM-EP75 (EP75) and vB_EcoP-EP335 (EP335) specifically infect Shiga toxin (Stx)-producing Escherichia coli (STEC) O157 strains. EP75 has a genome size of 158,143 bp and belongs to the genus Vi1virus The genome size of EP335 is 76,622 bp, and ...
Fieseler, Lars, Hagens, Steven, Klamert, Silvia, van de Straat, Leoni, van Mierlo, Joël, Witte, Sander   +5 more
core   +1 more source

Membrane invagination induced by Shiga toxin B-subunit: from molecular structure to tube formation.

Soft Matter, 2016
The bacterial Shiga toxin is composed of an enzymatically active A-subunit, and a receptor-binding homopentameric B-subunit (STxB) that mediates intracellular toxin trafficking.
W. Pezeshkian, W. Pezeshkian, Allan Grønhøj Hansen, Ludger Johannes, Ludger Johannes, Ludger Johannes, H. Khandelia, Julian C. Shillcock, Pawan Kumar, J. Ipsen   +9 more
semanticscholar   +1 more source

Realgar‐Induced CNS Toxicity: Exploring OTC‐Mediated Ornithine Regulation of ZBTB7A Inhibits Astrocyte Glycolysis Based on the Liver–Brain Axis

Advanced Science, Volume 13, Issue 2, 9 January 2026.
Arsenic in realgar induces CNS toxicity through direct and indirect effects: it activates ZBTB7A in astrocytes, which in turn inhibits glycolysis and impairs mice's learning, memory, and exploration; it also suppresses OTC in the liver to block the ornithine cycle, leading to blood ornithine accumulation that crosses into the frontal lobe and further ...
Ping Ye, Zhen Li, Huanyong Fu, Shuai Wang, Xingang Cui, Chengbo Song, Chao Ma, Hong Jiang   +7 more
wiley   +1 more source

Shiga Toxins: Intracellular Trafficking to the ER Leading to Activation of Host Cell Stress Responses

Toxins, 2010
Despite efforts to improve hygenic conditions and regulate food and drinking water safety, the enteric pathogens, Shiga toxin-producing Escherichia coli (STEC) and Shigella dysenteriae serotype 1 remain major public health concerns due to widespread ...
Moo-Seung Lee, Rama P. Cherla, Vernon L. Tesh   +2 more
doaj   +1 more source

Genetic diversity and pathogenic potential of Shiga toxin-producing Escherichia coli (STEC) derived from German flour

, 2021
Michaela Projahn, Marina C. Lamparter, Petra Ganas, André Goehler, Sandra C. Lorenz-Wright, Dietrich Maede, Angelika Fruth, Christina Lang, Elisabeth Schuh   +8 more
openalex   +1 more source

Enterohemorrhagic Escherichia coli infection inhibits colonic thiamin pyrophosphate uptake via transcriptional mechanism. [PDF]

, 2019
Colonocytes possess a specific carrier-mediated uptake process for the microbiota-generated thiamin (vitamin B1) pyrophosphate (TPP) that involves the TPP transporter (TPPT; product of the SLC44A4 gene).
Anandam, Kasin Yadunandam, Sabui, Subrata, Said, Hamid M, Subramanian, Sreya, Thompson, Morgan M   +4 more
core   +1 more source

Characterization of Shiga Toxin Subtypes and Virulence Genes in Porcine Shiga Toxin-Producing Escherichia coli

Frontiers in Microbiology, 2016
Similar to ruminants, swine have been shown to be a reservoir for Shiga toxin-producing Escherichia coli (STEC), and pork products have been linked with outbreaks associated with STEC O157 and O111:H-.
G. Baranzoni, P. Fratamico, J. Gangiredla, I. Patel, L. Bagi, S. Delannoy, P. Fach, Federica Boccia, A. Anastasio, T. Pepe   +9 more
semanticscholar   +1 more source

Potential Survival Benefit of Adjuvant Chemotherapy in Stage IV Intrahepatic Cholangiocarcinoma: A Multicenter, Stage‐Stratified Analysis

Annals of Gastroenterological Surgery, Volume 10, Issue 1, Page 241-250, January 2026.
This multicenter study suggests that adjuvant chemotherapy may improve survival in stage IV intrahepatic cholangiocarcinoma after resection, with S‐1 showing a potential survival advantage. ABSTRACT Background The survival benefit of adjuvant chemotherapy (AC) in intrahepatic cholangiocarcinoma (ICC) remains uncertain, particularly in advanced‐stage ...
Hisashi Kosaka, Masaki Ueno, Hiroji Shinkawa, Yusuke Yamamoto, Masahiko Kinoshita, Koji Komeda, Tsukasa Aihara, Satoshi Yasuda, Haruki Mori, Masaki Kaibori   +9 more
wiley   +1 more source

Multiplex PCR detection of stx1, stx2 and eaeA genes in Escherichia coli isolated from lambs in ChaharmahalvaBakhtiari, Iran

Biological Journal of Microorganism, 2013
Introduction: Pathogens can be transmitted to the humans through the consumption of contaminated meat and thus causing disease. Shiga-toxin-producing Escherichia coli can cause mild watery diarrhea to more serious complications of hemorrhagic colitis ...
Marzieh Tadi Beni, Vida Najafzadeh, Hossein Kaboli Boroujeni, Naser Khosravi, Hassan Momtaz, Hossein Tahmasby, Samaneh Mehrabiyan, Farnoush Ansari   +7 more
doaj  

Pathogenic Potential to Humans of Bovine Escherichia coli O26, Scotland [PDF]

, 2012
Escherichia coli O26 and O157 have similar overall prevalences in cattle in Scotland, but in humans, Shiga toxin–producing E. coli O26 infections are fewer and clinically less severe than E. coli O157 infections.
Allison, L.J., Caprioli, A., Chase-Topping, M.E., Courcier, E., Evans, J., Gally, D.L., Handel, I., Hanson, M.F., Karch, H., Locking, M.E., Low, J.C., Matthews, L., McKendrick, I.J., Pearce, M.C., Pollock, K.J., Rosser, T., Woolhouse, M.E.J.   +16 more
core   +5 more sources