Signs and symptoms of Shiga toxin–producing Escherichia coli (STEC) serogroup O157:H7 infection range from mild gastrointestinal to bloody diarrhea and hemolytic uremic syndrome (HUS).
L. Byrne, N. Adams, C. Jenkins
semanticscholar +1 more source
Shiga Toxin: Expression, Distribution, and Its Role in the Environment
In this review, we highlight recent work that has increased our understanding of the production and distribution of Shiga toxin in the environment. Specifically, we review studies that offer an expanded view of environmental reservoirs for Shiga toxin ...
Steven A. Mauro, Gerald B. Koudelka
doaj +1 more source
Open-source genomic analysis of Shiga-toxin–producing E. coli O104:H4 [PDF]
An outbreak caused by Shiga-toxin–producing Escherichia coli O104:H4 occurred in Germany in May and June of 2011, with more than 3000 persons infected. Here, we report a cluster of cases associated with a single family and describe an open-source genomic
Antoine Danchin +39 more
core +1 more source
Recently, the Aquaponic Association (AA) published a statement through multiple outlets in response to our article entitled “The Occurrence of Shiga Toxin-Producing E. coli in Aquaponic and Hydroponic Systems” [...]
Yi-Ju Wang, A. Deering, Hye-Ji Kim
semanticscholar +1 more source
Syntaxin 16 and syntaxin 5 are required for efficient retrograde transport of several exogenous and endogenous cargo proteins [PDF]
Retrograde transport allows proteins and lipids to leave the endocytic pathway to reach other intracellular compartments, such as trans-Golgi network (TGN)/Golgi membranes, the endoplasmic reticulum and, in some instances, the cytosol. Here, we have used
Amessou, Mohamed +7 more
core +1 more source
Regional Differences in Presence of Shiga toxin-producing Escherichia coli Virulence-Associated Genes in the Environment in the North West and East Anglian regions of England [PDF]
Shiga toxin-producing Escherichia coli is carried in the intestine of ruminant animals, and outbreaks have occurred after contact with ruminant animals or their environment.
Hunter, Paul R +6 more
core +1 more source
Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS
Shiga toxin, a phage-encoded bacterial virulence factor, inhibits caspase-11–mediated inflammasome responses. Paring down pyroptosis Shiga toxin is a phage-encoded exotoxin that interrupts protein translation and functions as a virulence factor for ...
Morena S. Havira +7 more
semanticscholar +1 more source
Down-Regulation of Renal Klotho Expression by Shiga Toxin 2
Background/Aims: Shiga toxin 2 may trigger classical hemolytic uremic syndrome (HUS) eventually leading to renal failure. Klotho, a transmembrane protein, protease and hormone mainly expressed in kidney is involved in the regulation of renal phosphate ...
Martina Feger +7 more
doaj +1 more source
Early termination of the Shiga toxin transcript generates a regulatory small RNA
Significance Enterohemorrhagic E. coli is a significant human pathogen that can cause severe disease due to the release of Shiga toxins. The toxins are encoded within lysogenic bacteriophage and controlled by antitermination of the phage late promoter ...
Brandon M. Sy, R. Lan, J. Tree
semanticscholar +1 more source
Laboratory Practices and Incidence of Non-O157 Shiga Toxin–producing Escherichia coli Infections
We surveyed laboratories in Washington State, USA, and found that increased use of Shiga toxin assays correlated with increased reported incidence of non-O157 Shiga toxin–producing Escherichia coli (STEC) infections during 2005–2010.
Kathleen A. Stigi +3 more
doaj +1 more source

