Regional Differences in Presence of Shiga toxin-producing Escherichia coli Virulence-Associated Genes in the Environment in the North West and East Anglian regions of England [PDF]
Shiga toxin-producing Escherichia coli is carried in the intestine of ruminant animals, and outbreaks have occurred after contact with ruminant animals or their environment.
Hunter, Paul R +6 more
core +1 more source
The provisional molecular approach, proposed by EFSA in 2013, for the pathogenicity assessment of Shiga toxin-producing Escherichia coli (STEC) has been reviewed.
K. Koutsoumanis +23 more
semanticscholar +1 more source
Recent Updates on Outbreaks of Shiga Toxin-Producing Escherichia coli and Its Potential Reservoirs
Following infection with certain strains of Shiga toxin-producing Escherichia coli (STEC), particularly enterohemorrhagic ones, patients are at elevated risk for developing life-threatening extraintestinal complications, such as acute renal failure ...
Jun-Seob Kim +2 more
semanticscholar +1 more source
Functional Dissection of the Retrograde Shiga Toxin Trafficking Inhibitor Retro-2
The retrograde transport inhibitor Retro-2 has a protective effect on cells and in mice against Shiga-like toxins and ricin. Retro-2 causes toxin accumulation in early endosomes and relocalization of the Golgi SNARE protein syntaxin-5 to the endoplasmic ...
A. Forrester +19 more
semanticscholar +1 more source
Signs and symptoms of Shiga toxin–producing Escherichia coli (STEC) serogroup O157:H7 infection range from mild gastrointestinal to bloody diarrhea and hemolytic uremic syndrome (HUS).
L. Byrne, N. Adams, C. Jenkins
semanticscholar +1 more source
Recently, the Aquaponic Association (AA) published a statement through multiple outlets in response to our article entitled “The Occurrence of Shiga Toxin-Producing E. coli in Aquaponic and Hydroponic Systems” [...]
Yi-Ju Wang, A. Deering, Hye-Ji Kim
semanticscholar +1 more source
Shiga toxin suppresses noncanonical inflammasome responses to cytosolic LPS
Shiga toxin, a phage-encoded bacterial virulence factor, inhibits caspase-11–mediated inflammasome responses. Paring down pyroptosis Shiga toxin is a phage-encoded exotoxin that interrupts protein translation and functions as a virulence factor for ...
Morena S. Havira +7 more
semanticscholar +1 more source
Revisiting the STEC Testing Approach: Using espK and espV to Make Enterohemorrhagic Escherichia coli (EHEC) Detection More Reliable in Beef [PDF]
Current methods for screening Enterohemorrhagic Escherichia coli (EHEC) O157 and non-O157 in beef enrichments typically rely on the molecular detection of stx, eae, and serogroup-specific wzx or wzy gene fragments.
Beutin, Lothar +7 more
core +4 more sources
Laboratory Practices and Incidence of Non-O157 Shiga Toxin–producing Escherichia coli Infections
We surveyed laboratories in Washington State, USA, and found that increased use of Shiga toxin assays correlated with increased reported incidence of non-O157 Shiga toxin–producing Escherichia coli (STEC) infections during 2005–2010.
Kathleen A. Stigi +3 more
doaj +1 more source
Early termination of the Shiga toxin transcript generates a regulatory small RNA
Significance Enterohemorrhagic E. coli is a significant human pathogen that can cause severe disease due to the release of Shiga toxins. The toxins are encoded within lysogenic bacteriophage and controlled by antitermination of the phage late promoter ...
Brandon M. Sy, R. Lan, J. Tree
semanticscholar +1 more source

