Results 61 to 70 of about 366,512 (248)
Ricin trafficking in plant and mammalian cells [PDF]
Ricin is a heterodimeric plant protein that is potently toxic to mammalian and many other eukaryotic cells. It is synthesized and stored in the endosperm cells of maturing Ricinus communis seeds (castor beans).
Lord, Mike, Spooner, Robert A.
core +2 more sources
Non-O157 strains of Shiga toxin-producing Escherichia coli (STEC) are more common causes of acute diarrhea than the better-known O157 strains and have the potential for large outbreaks.
Evangelia Valilis +3 more
semanticscholar +1 more source
Replication of plasmids derived from Shiga toxinconverting bacteriophages in starved Escherichia coli [PDF]
The pathogenicity of Shiga toxin-producing Escherichia coli (STEC) depends on the expression of stx genes that are located on lambdoid prophages. Effective toxin production occurs only after prophage induction, and one may presume that replication of the
Nadratowska-Wesołowska, Beata +4 more
core
BACKGROUND AND OBJECTIVES Inherited complement hyperactivation is critical for the pathogenesis of atypical hemolytic uremic syndrome (HUS) but undetermined in postdiarrheal HUS. Our aim was to investigate complement activation and variants of complement
V. Frémeaux-Bacchi +16 more
semanticscholar +1 more source
Cutaneous and renal glomerular vasculopathy as a cause of acute kidney injury in dogs in the UK [PDF]
To describe the signalment, clinicopathological findings and outcome in dogs presenting with acute kidney injury (AKI) and skin lesions between November 2012 and March 2014, in whom cutaneous and renal glomerular vasculopathy (CRGV) was suspected and ...
ARDISSINO +46 more
core +1 more source
Shiga toxin binds to activated platelets [PDF]
Hemolytic uremic syndrome (HUS) is associated with acute renal failure in children and can be caused by Shiga toxin (Stx)-producing Escherichia coli. Thrombocytopenia and formation of renal thrombi are characteristic of HUS, suggesting that platelet activation is involved in its pathogenesis. However, whether Shiga toxin directly activates platelets is
S A, Ghosh +4 more
openaire +2 more sources
Enterohemorrhagic Escherichia coli (EHEC) produces Shiga toxin 1 (Stx1) and Shiga toxin 2 (Stx2). Nitric oxide (NO), which acts as an antimicrobial defense molecule, was found to enhance the production of Stx1 and Stx2 in EHEC under anaerobic conditions.
Kimitoshi Ichimura +7 more
doaj +1 more source
Top-down and middle-down proteomic analysis of Shiga toxin using MALDI-TOF-TOF mass spectrometry
The method describes a step-by-step process for analysis of putative Shiga toxin-producing Escherichia coli (STEC) for expression of Shiga toxin (Stx).
Clifton K. Fagerquist +1 more
doaj +1 more source
Pathologic changes in mice induced by subtilase cytotoxin, a potent new Escherichia coli AB(5) toxin that targets the endoplasmic reticulum [PDF]
Subtilase cytotoxin (SubAB) is the prototype of a recently discovered AB₅ cytotoxin family produced by certain strains of Shiga toxigenic Escherichia coli (STEC).
Paton, A., Paton, J., Wang, H.
core +1 more source
Geogenomic segregation and temporal trends of human pathogenic Escherichia coli o157:H7, Washington, USA, 2005-2014 [PDF]
The often-noted and persistent increased incidence of Escherichia coli O157:H7 infections in rural areas is not well understood. We used a cohort of E.
Besser, Thomas E +8 more
core +2 more sources

