Results 71 to 80 of about 180,202 (208)

Shiga Toxin-Bearing Microvesicles Exert a Cytotoxic Effect on Recipient Cells Only When the Cells Express the Toxin Receptor

Frontiers in Cellular and Infection Microbiology, 2020
Shiga toxin is the main virulence factor of non-invasive enterohemorrhagic Escherichia coli strains capable of causing hemolytic uremic syndrome. Our group has previously shown that the toxin can reach the kidney within microvesicles where it is taken up
Karl Johansson, Annie Willysson, Ann-Charlotte Kristoffersson, Ashmita Tontanahal, Daniel Gillet, Anne-lie Ståhl, Diana Karpman   +6 more
doaj   +1 more source

Sequential Regulation of Neurovascular Bone Regeneration in Large Bone Defects Using Black Phosphorus‐Europium Nanosheet Integrated TPMS Biomimetic Scaffold with Photo‐Controlled Ion Release

Advanced Science, EarlyView.
TPBE scaffolds, in conjunction with mild photothermal effects, effectively activate the PI3K/Akt signaling cascade, thereby promoting early neuronal differentiation and neurite growth. Short‐term (12 W) in vivo implantation studies revealed no significant pathological damage to major organs, providing preliminary evidence of the material's excellent ...
Bingqian Wang, Yuping Zhang, Xiaoning Su, Ning Liu, Hui Zeng, Bo Yang, Yang Xue, Fang Guo, Changkui Liu   +8 more
wiley   +1 more source

Timeliness of Surveillance during Outbreak of Shiga Toxin–producing Escherichia coli Infection, Germany, 2011

Emerging Infectious Diseases, 2011
In the context of a large outbreak of Shiga toxin–producing Escherichia coli O104:H4 in Germany, we quantified the timeliness of the German surveillance system for hemolytic uremic syndrome and Shiga toxin–producing E.
Mathias Altmann, Anke Spode, Doris Altmann, Maria Wadl, Justus Benzler, Tim Eckmanns, Gérard Krause, Matthias an der Heiden   +7 more
doaj   +1 more source

Genetic and Chemical Genetic Approaches to Shiga Toxin Inhibition [PDF]

, 2011
Infection with Shiga toxin-producing bacteria can place patients at risk of developing hemolytic uremic syndrome, a toxemic condition characterized by hemolytic anemia, thrombocytopenia, and acute renal failure.
Saenz, Jose
core   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

Practical Review on Aetio-Pathogenesis and Symptoms in Pigs Affected by Clinical and Subclinical Oedema Disease and the Use of Commercial Vaccines Under Field Conditions

Animals
The impact of Oedema Disease produced by Shiga toxigenic Escherichia coli (STEC) in swine is increasing in some production countries due to increasing limitations on treatment with antimicrobials and zinc oxide, either because of the increased prevalence
Juan Hernandez-Garcia, Isaac Ballarà Rodriguez, Ramon Jordà Casadevall, Sergi Bruguera, David Llopart, Emili Barba-Vidal   +5 more
doaj   +1 more source

Top-Down Proteomic Identification of Shiga Toxin 1 and 2 from Pathogenic Escherichia coli Using MALDI-TOF-TOF Tandem Mass Spectrometry

Microorganisms, 2019
Shiga-toxin-producing Escherichia coli (STEC) are a burden on agriculture and a threat to public health. Rapid methods are needed to identify STEC strains and characterize the Shiga toxin (Stx) they produce.
Clifton K. Fagerquist, William J. Zaragoza, Michelle Q. Carter   +2 more
doaj   +1 more source

Microangiopathic Anemia without Thrombocytopenia and Kidney Disease in a Child with Diarrhea Caused by Shiga Toxin–Producing Escherichia coli [PDF]

, 2004
A child with a history of diarrhea presented with transient anemia, reticolucytosis, and red blood cell fragmentation. Blood pressure and levels of blood platelets, creatinine, and urea were normal, as were results of urinalysis.
Rudin, C., von der Weid, N. X., Rudin, Christoph, Meier, P. W., Bianchetti, Mario G., Bianchetti, M. G., Meier, Paul W., Pachlopnik, Jana M., Von Der Weid, Nicolas X., Pachlopnik, J. M.   +9 more
core   +2 more sources

Structure-Activity Relationship Studies of Retro-1 Analogues Against Shiga Toxin [PDF]

, 2020
The Retro-1 molecule was identified in a high-throughput screening as an inhibitor of ricin and Shiga toxins by diminishing their intracellular trafficking via the retrograde route, from early endosomes to the Golgi apparatus.
Valérie, Pons, David-Alexandre, Buisson, Jean-Christophe, Cintrat, Daniel, Gillet, Lilia, Ait Ouarab, Lucie, Caramelle, Aurélien, Michau, Julien, Barbier, Hajer, Abdelkafi, Flora, Ngadjeua, Alexandra, Clerget   +10 more
core   +1 more source

Postharvest Survival of Foodborne Pathogens on Strawberry Surfaces at Different Maturity Levels

Food Safety and Health, EarlyView.
This study highlights the survival of E. coli and L. monocytogenes on strawberries at different maturity stages and storage temperatures. Predictive microbial modeling revealed temperature‐ and ripeness‐dependent survival trends, emphasizing the importance of temperature control and ripeness in developing effective strategies to enhance strawberry ...
Prachi Pahariya, Derek J. Fisher, Abhinav Mishra, Ruplal Choudhary   +3 more
wiley   +1 more source