A food chain approach to control of Shiga toxin-producing Escherichia coli in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand [PDF]
, 2018 Part of Chapter 3 has been published as: Browne, A.S., Midwinter, A.C., Withers, H., Cookson, A.L., Biggs, P.J., Marshall J.C., Benschop, J., Hathaway, S., Haack, N., Akhter, R., & French, N.P. (2018).
Browne, Andrew Springer
core
Geogenomic segregation and temporal trends of human pathogenic Escherichia coli o157:H7, Washington, USA, 2005-2014 [PDF]
, 2018 The often-noted and persistent increased incidence of Escherichia coli O157:H7 infections in rural areas is not well understood. We used a cohort of E.
Besser, Thomas E +8 more
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Cancer Science, EarlyView.Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...
Shigenori Suzuki +14 more
wiley +1 more source
Targeting the Early Endosome-to-Golgi Transport of Shiga Toxins as a Therapeutic Strategy
Toxins, 2020 Shiga toxin (STx) produced by Shigella and closely related Shiga toxin 1 and 2 (STx1 and STx2) synthesized by Shiga toxin-producing Escherichia coli (STEC) are bacterial AB5 toxins.
Danyang Li +2 more
doaj +1 more source
"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]
, 2007 Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
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Cancer Science, EarlyView.While CAFs are produced as a result of education by cancer cells in non‐scirrhous gastric cancer, normal fibroblasts of scirrhous gastric cancer patients are already pre‐conditioned, forming a stromal field for scirrhous gastric cancer. ABSTRACT Scirrhous gastric cancer has aggressive clinical courses and is characterized by dominating cancer ...
Yoshimi Yasukawa +12 more
wiley +1 more source
Scientific Reports, 2023 An important challenge relating to clinical diagnostics of the foodborne pathogen Shiga toxin-producing E. coli (STEC), is that PCR-detection of the shiga-toxin gene (stx) in DNA from stool samples can be accompanied by a failure to identify an STEC ...
Hege S. Tunsjø +2 more
doaj +1 more source
Frontiers in Microbiology, 2023 IntroductionShiga toxin-producing Escherichia coli (STEC) is a gastrointestinal pathogen causing foodborne outbreaks. Whole Genome Sequencing (WGS) in STEC surveillance holds promise in outbreak prevention and confinement, in broadening STEC epidemiology
Stéphanie Nouws +11 more
doaj +1 more source
Enterohemorrhagic Escherichia coli with particular attention to the German outbreak strain O104:H4 [PDF]
, 2012 This review deals with the epidemiology and ecology of enterohemorrhagic Escherichia coli (EHEC), a subset of the verocytotoxigenic Escherichia coli (VTEC), and subsequently discusses its public health concern.
De Reu, K +4 more
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The long polar fimbriae (lpf) operon and its flanking regions in bovine Escherichia coli O157:H43 and STEC O136:H12 strains [PDF]
, 2013 Long polar fimbriae (Lpf) are intestinal adhesins and important virulence factors of pathogenic Escherichia coli strains. We cloned and sequenced the lpf2-1 operon (lpf2ABCD) and its flanking regions of an intimin- and Shiga toxin-negative E.
Dobrindt, Ulrich +7 more
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