Results 91 to 100 of about 180,202 (208)

Shiga Toxins: Intracellular Trafficking to the ER Leading to Activation of Host Cell Stress Responses

Toxins, 2010
Despite efforts to improve hygenic conditions and regulate food and drinking water safety, the enteric pathogens, Shiga toxin-producing Escherichia coli (STEC) and Shigella dysenteriae serotype 1 remain major public health concerns due to widespread ...
Moo-Seung Lee, Rama P. Cherla, Vernon L. Tesh   +2 more
doaj   +1 more source

Synthesis of Chiral Gold Nanostructures on Gold‐Coral‐Coated Transparent Conductive Oxide Substrates via [AuCl4]– and Cysteine Interactions for Enhanced Chiral Sensing

Small, EarlyView.
We developed hierarchical chiral Au nanostructures on Au coral structures on transparent conductive oxide substrates using only electrochemical methods. By controlling the interaction between [AuCl4]– and cysteine, we successfully tuned the morphology and circular dichroism of the resulting Au nanostructures.
Kenta Nakagawa, Junhe Wang, Tianji Zhang, Yuta Shiga, Olga Guselnikova, Takuya Nakanishi, Yusuke Yamauchi, Toru Asahi   +7 more
wiley   +1 more source

Extracellular vesicles in Shiga toxin-mediated disease [PDF]

, 2021
Extracellular vesicles are released during infectious, inflammatory and prothrombotic conditions. These are membrane-derived vesicles shed by cells during activation, senescence and/or apoptosis.
Willysson, Annie
core  

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

A Comprehensive Review on Shiga Toxin Subtypes and Their Niche-Related Distribution Characteristics in Shiga-Toxin-Producing E. coli and Other Bacterial Hosts

Microorganisms
Shiga toxin (Stx), the main virulence factor of Shiga-toxin-producing E. coli (STEC), was first discovered in Shigella dysenteriae strains. While several other bacterial species have since been reported to produce Stx, STEC poses the most significant ...
Xuan Wang, Daniel Yu, Linda Chui, Tiantian Zhou, Yu Feng, Yuhao Cao, Shuai Zhi   +6 more
doaj   +1 more source

Phylogenetic analysis of Shiga toxin 1 and Shiga toxin 2 genes associated with disease outbreaks-0

, 2011
Copyright information:Taken from "Phylogenetic analysis of Shiga toxin 1 and Shiga toxin 2 genes associated with disease outbreaks"http://www.biomedcentral.com/1471-2180/7/109BMC Microbiology 2007;7():109-109.Published online 4 Dec 2007PMCID:PMC2211750.
Larry D Farrell (66913), Peter P Sheridan (27773), James E Lee (66909), Junelina Reed (66910), Malcolm S Shields (66911), Kathleen M Spiegel (66912)   +5 more
core   +1 more source

A Three‐Dimensional Culture–Drug Sensitivity Test Predicts MDM2 Inhibitor–Sensitivity in SMARCB1/INI1‐Deficient Tumors

Cancer Science, EarlyView.
This study aimed to determine whether personalized selection of effective drugs for SMARCB1/INI1‐deficient tumors is feasible using in vitro drug sensitivity profiling. Drug sensitivity was assessed using a short‐term collagen gel–embedded three‐dimensional drug sensitivity test (3D‐DST) in tumors derived from SMARCB1/INI1‐deficient tumor cell line ...
Hiroaki Goto, Chiyoko Nishime, Takashi Ohtsu, Mieko Ito, Maiko Sagisaka, Takuya Naruto, Norihiko Kitagawa, Mio Tanaka, Masakatsu Yanagimachi, Yukihiko Hiroshima, Junko Takita, Yasuhide Hayashi, Yohei Miyagi   +12 more
wiley   +1 more source

Phylogenetic analysis of Shiga toxin 1 and Shiga toxin 2 genes associated with disease outbreaks-3

, 2011
Copyright information:Taken from "Phylogenetic analysis of Shiga toxin 1 and Shiga toxin 2 genes associated with disease outbreaks"http://www.biomedcentral.com/1471-2180/7/109BMC Microbiology 2007;7():109-109.Published online 4 Dec 2007PMCID:PMC2211750.
Larry D Farrell (66913), Peter P Sheridan (27773), James E Lee (66909), Junelina Reed (66910), Malcolm S Shields (66911), Kathleen M Spiegel (66912)   +5 more
core   +1 more source

Targeted Photo‐Induced Elimination of Tumor‐Associated Macrophages Suppresses Cancer Progression in a Murine Model

Cancer Science, EarlyView.
This study demonstrates the selective depletion of tumor‐associated macrophages (TAMs) by targeting CSF1R through near‐infrared photoimmunotherapy (NIR‐PIT). Using a combination of anti‐CSF1R Fab‐IR700 conjugates and localized light irradiation, we achieved tumor suppression and durable antitumor immunity without systemic toxicity.
Kohei Nakajima, Tomomi Uchiyama, Kazuki Funayama, Yuto Goto, Akari Mukaimine, Naoya Ieda, Mikako Ogawa   +6 more
wiley   +1 more source

Clinical Isolates of Shiga Toxin 1a–Producing Shigella flexneri with an Epidemiological Link to Recent Travel to Hispañiola

Emerging Infectious Diseases, 2014
Shiga toxins (Stx) are cytotoxins involved in severe human intestinal disease. These toxins are commonly found in Shigella dysenteriae serotype 1 and Shiga-toxin–producing Escherichia coli; however, the toxin genes have been found in other Shigella ...
Miranda D. Gray, Keith A. Lampel, Nancy A. Strockbine, Reinaldo E. Fernandez, Angela R. Melton-Celsa, Anthony T. Maurelli   +5 more
doaj   +1 more source