Results 291 to 300 of about 182,022 (327)

Targeted Anti‐Inflammatory Therapy in Cardiovascular Events: Challenges and Opportunities

The Journal of Clinical Hypertension, Volume 27, Issue 11, November 2025.
ABSTRACT Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality globally. Emerging evidence suggests that inflammation plays a pivotal role in the pathogenesis of atherosclerosis and subsequent cardiovascular events. Traditional treatments primarily focus on lipid‐lowering and antithrombotic strategies; however, these ...
Li Feng, Ling Wang, Xiaorong Yan, Tianyi Ma   +3 more
wiley   +1 more source

Intratumorally specific microbial-derived lipopolysaccharide contributes to non-small cell lung cancer progression. [PDF]

Virulence
Sha G, Wu Z, Wang B, Ding Y, Xiao Z, Zhang W, Zhou J, Zhou Y, Ji G, Tian Z, Zhang W, Zhao X.   +11 more
europepmc   +1 more source

Enterococcus faecalis Translocation in Sepsis: Fibrinolysis and Mitochondrial Dysfunction Drive Lung Injury

Journal of Cellular and Molecular Medicine, Volume 29, Issue 21, November 2025.
ABSTRACT Sepsis frequently progresses to acute lung injury (ALI), characterised by inflammation, extracellular matrix degradation, and mitochondrial dysfunction. This study identifies Enterococcus faecalis as a gut‐derived bacterium that exploits the host fibrinolytic system for pulmonary translocation, resulting in mitochondrial damage and ...
Chenfei Wang, Dan Lv, Yuan Gao, Xinhui Xu, Changqing Zhu, Song Zhang, Keji Zhang   +6 more
wiley   +1 more source

Correlation of fecal calprotectin levels with the detection of treatable enteric pathogens in children with severe acute diarrheal disease in Botswana. [PDF]

PLoS One
Rehan M, MacBain E, Shajib MS, Mokomane M, Lechiile K, Arscott-Mills T, Steenhoff AP, Mazhani L, Main C, Smieja M, Khan WI, Goldfarb DM, Pernica JM.   +12 more
europepmc   +1 more source

En route vers des glycoconjugués à potentiel vaccinal contre la dysenterie bacillaire : synthèse d'oligosaccharides représentatifs de l'antigène O de Shigella flexneri sérotype 6

, 2012
Pierre Chassagne
openalex   +1 more source

Shigella-trained pro-inflammatory macrophages protect zebrafish from secondary infection

Margarida C. Gomes, Dominik Brokatzky, Serge Mostowy   +2 more
openalex   +1 more source

A Small RNA Derived From the 5′ End of the IS200 tnpA Transcript Regulates Multiple Virulence Regulons in Salmonella typhimurium

Molecular Microbiology, Volume 124, Issue 5, Page 413-432, November 2025.
We show deletion of an IS200‐encoded sRNA (5′tnpA) in Salmonella impacts the expression of SPI‐1, flagellar, cysteine, and phsABC regulons. Evidence is presented that, with regard to the SPI‐1 regulon, 5′tnpA may function through base pairing with another sRNA known to regulate SPI1 called PinT.
Ryan S. Trussler, Naomi‐Jean Q. Scherba, Hoda Kooshapour, Michael J. Ellis, Konrad U. Förstner, Matthew Albert, Alexander J. Westermann, David B. Haniford   +7 more
wiley   +1 more source

The emergence of sexually transmissible <i>Shigella flexneri</i> serotype 1b between 2019 and 2024 in England: a descriptive epidemiological study. [PDF]

Microb Genom
Robinson A, Rodwell EV, Verlander NQ, Charles H, Baker KS, Chattaway MA, Jenkins C.   +6 more
europepmc   +1 more source

Etude du système de sécrétion de type III de Shigella: contact cellulaire, hiérarchie de sécrétion et propriétés antigéniques

, 2015
Lionel Schiavolin, Philippe Lebrun, Laurence Van Melderen   +2 more
openalex   +1 more source

A new paradigm of bacteria-gut interplay brought through the study of <bold>Shigella</bold>

, 2010
Chihiro Sasakawa
openalex   +2 more sources