Results 61 to 70 of about 177,811 (299)

Neutropenia as an adverse event following vaccination : results from randomized clinical trials in healthy adults and systematic review [PDF]

, 2016
Background : In the context of early vaccine trials aimed at evaluating the safety profile of novel vaccines, abnormal haematological values, such as neutropenia, are often reported.
Aerssens, Annelies, Anemona, Alessandra, Bodinham, Caroline L, Groth, Nicola, Launay, Odile, Leroux-Roels, Geert, Lewis, David, Loulergue, Pierre, Muturi-Kioi, Vincent, Podda, Audino, Saul, Allan   +10 more
core   +4 more sources

Burden of enterotoxigenic Escherichia coli and shigella non-fatal diarrhoeal infections in 79 low-income and lower middle-income countries: a modelling analysis

Lancet Global Health, 2019
Summary Background Enterotoxigenic Escherichia coli (ETEC) and shigella are two major pathogens that cause moderate-to-severe diarrhoea in children younger than 5 years.
John D. Anderson, K. Bagamian, Farzana Muhib, Mirna P. Amaya, Lindsey A. Laytner, T. Wierzba, R. Rheingans   +6 more
semanticscholar   +1 more source

Mixed Evidence for Impact of Early Infant Gut Microbiome and Later Development of Autism Spectrum Disorder in the MARBLES Prospective Cohort Study

Autism Research, EarlyView.
ABSTRACT This study investigated the relationship between early infant gut microbiome composition and subsequent neurodevelopmental outcomes. Fecal samples from children in the markers of autism risks in babies‐learning early signs (MARBLES) study, a cohort with elevated likelihood of autism, were collected between 0 and 7 months of age and analyzed ...
Jennie Sotelo‐Orozco, Diana H. Taft, Jassim Al‐Oboudi, Brittany C. Baikie, Cailyn Lake, Meghan Miller, David A. Mills, Daniel J. Tancredi, Rebecca J. Schmidt, Irva Hertz‐Picciotto, Deborah H. Bennett   +10 more
wiley   +1 more source

Superficieibacter electus gen. nov., sp. nov., an extended-spectrum β-lactamase possessing member of the enterobacteriaceae family, isolated from Intensive Care Unit surfaces [PDF]

, 2018
Two Gram-negative bacilli strains, designated BP-1(T) and BP-2, were recovered from two different Intensive Care Unit surfaces during a longitudinal survey in Pakistan.
Andleeb, Saadia, Beatty, Wandy, Burnham, Carey-Ann D, D-Souza, Alaric W, Dantas, Gautam, Gul, Danish, Kwon, Jennie H, Patel, Sanket, Potter, Robert F, Shupe, Angela, Wallace, Meghan A   +10 more
core   +5 more sources

Prevalence and antimicrobial susceptibility of Salmonella and Shigella species isolated from diarrheic children in Ambo town

BMC Pediatrics, 2020
Diarrhea, particularly of enteric bacterial pathogen, remains a major cause of morbidity and mortality in Ethiopia. Despite the high prevalence of diarrheal disease among under-five children, antibiotic resistance of bacterial pathogens test is not part ...
Wagi Tosisa, A. Mihret, Asnake Ararsa, T. Eguale, T. Abebe   +4 more
semanticscholar   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Sustainable approaches for stormwater quality improvements with experimental geothermal paving systems [PDF]

, 2015
This article has been made available through the Brunel Open Access Publishing Fund.This research assesses the next generation of permeable pavement systems (PPS) incorporating ground source heat pumps (geothermal paving systems).
Clesceri, Hunter, Kiran Tota-Maharaj, Mac Berthouex, Newman, Parneet Paul, Scholz, Scholz, Tota-Maharaj, Tota-Maharaj, Van der Wel, Zhang   +11 more
core   +6 more sources

GMMA and Glycoconjugate Approaches Compared in Mice for the Development of a Vaccine against Shigella flexneri Serotype 6

Vaccines, 2020
Shigella infections are one of the top causes of diarrhea throughout the world, with Shigella flexneri being predominant in developing countries. Currently, no vaccines are widely available and increasing levels of multidrug-resistance make Shigella a ...
M. M. Raso, G. Gasperini, R. Alfini, Fabiola Schiavo, M. G. Aruta, M. Carducci, Maria Concetta Forgione, S. Martini, P. Cescutti, F. Necchi, F. Micoli   +10 more
semanticscholar   +1 more source

Deciphering the catalytic and pharmacological mechanisms of Coptis chinensis herbzymes to renovate intestinal microenvironment for colitis alleviation

BMEMat, EarlyView.
The synthesized CCzymes possess both antioxidant enzyme activity and pharmacological properties inherent to Coptis chinensis. By their antioxidant enzyme activity, CCzymes can attenuate oxidative stress within the inflammatory region of ulcerative colitis (UC), while their pharmacological activity acts on macrophage polarization and the intestinal ...
Zhichao Deng, Can Li, Yujie Zhang, Yuanyuan Zhu, Chenxi Xu, Bowen Gao, Mingxin Zhang, Martina H. Stenzel, Kelong Fan, Mingzhen Zhang, Yanyan Jiang   +10 more
wiley   +1 more source

Eudragit®‐engineered pH‐responsive probiotic microspheres with enhanced gastrointestinal resistance and prolonged storage stability for inflammatory bowel disease therapy

BMEMat, EarlyView.
This study reports the development of AMS@Eud core‐shell microspheres, combining calcium alginate and pH‐responsive Eudragit® L100, which exhibit exceptional gastrointestinal resistance and long‐term storage stability (only 5.28%–9.09% viability loss over 35 days at 4–25°C), and effectively alleviate inflammatory bowel disease via gut microbiota ...
Ming Teng, Xiaomin Luo, Peng Zhang, Chen Yang, Yuniel Ma, Xinhua Liu   +5 more
wiley   +1 more source