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Shigella flexneri: an emerging pathogen

Folia Microbiologica, 2020
Shigella flexneri is a leading etiologic agent of diarrhea in low socioeconomic countries. Notably, various serotypes in S. flexneri are reported from different regions of the world. The precise approximations of illness and death owing to shigellosis are missing in low socioeconomic countries, although it is widespread in different regions.
Iqbal, Nisa   +4 more
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Shigella flexneri bacteraemia

Journal of Infection, 1985
Shigellosis is usually a non-invasive enteric disease, rarely accompanied by extra-intestinal manifestations. Shigella septicaemia is therefore reported in a child aged 10 months. In the laboratory the organism was resistant to ampicillin and only moderately susceptible to chloramphenicol.
A H, Chagla, K N, Haque, A M, Kambal
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Lambda Red Recombineering in Shigella flexneri

2022
Shigellosis remains a major cause of severe diarrheal disease and death throughout the world. Vaccine development against shigellosis has been hampered by an incomplete understanding of the molecular mechanisms by which Shigella spp. causes disease and difficulties in manipulating Shigella spp. genomes.
Adrian, Herod, Julie, Ryu, John, Rohde
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Shigella flexneri Diguanylate Cyclases Regulate Virulence

Journal of Bacteriology, 2021
The intracellular human pathogen Shigella causes dysentery, resulting in as many as one million deaths per year. Currently, there is no approved vaccine for the prevention of shigellosis, and the incidence of antimicrobial resistance among Shigella species is on the rise.
Ruchi Ojha   +3 more
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Contrasting epidemiology of shigellae dysenteriae and shigellae flexneri, Dacca

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1980
Abstract To characterize the epidemiological contrast between Shigella dysenteriae type 1, Sh. flexneri and dysentery-like control families, a 10-day follow-up study has been conducted in Dacca areas where Sh. flexneri and Sh. dysenteriae type 1 were the two most prevalent types. In children (0–9), the secondary infection rates were 29·3% in
M, Khan, M, Shahidullah
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IcsA (Shigella flexneri)

1997
Abstract Shigella flexneri, the causative agent of bacillary dysentery, is a facultative intracellular pathogen that can enter and spread inside the host epithelial cells. This invasion process involves a sequence of molecular interactions between bacterial virulence factors and the host cell cytoskeleton (Sansonetti et al. 1994).
C Egile, P J Sansonetti
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LABORATORY INFECTIONS WITH SHIGELLA FLEXNERI 3 AND SHIGELLA SONNEI

Journal of the American Medical Association, 1954
Surveys by Sulkin and Pike revealed 31 cases of shigellosis among laboratory workers, but only two of these cases had been reported in the literature. The earliest record of bacillary dysentery contracted in the laboratory may be attributed to Hirschburch and Theim in 1918 (cited by Boyd, 1940). Lippincott published a brief description of an accidental
L S, SUTTON, A J, SHANAHAN
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Corneal Ulceration Due to Shigella Flexneri

Journal of Pediatric Ophthalmology & Strabismus, 1980
Shigella keratitis with ulceration is a rare occurrence with only four previous reports in the literature. Corneal ulceration appears to be characteristically superficial with a predilection for the inferior cornea. In the case reported here, resolution of ulceration occurred with the use of gentamicin and chloramphenicol, following a poor response to ...
M, Kelinske, R, Poirier
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Encéphalopathie fulminante à Shigella flexneri

Archives de Pédiatrie, 1996
Resume Les shiggelles sont responsables d'un syndrome dysenterique qui peut s'accompagner de signes neurologiques, viore d'une encephalopathie fulminante notamment en cas d'infection par Shigella flexneri ou sonnei . Observation — Une fillette âgee de 6 ans et demi a ete hospitalisee pour une diarrhee febrile evoluant depuis 24 heures et ...
S Dieu-Osika   +6 more
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