Results 21 to 30 of about 54,989 (228)

Immunization of Rabbits with a Quadrivalent Shigella Bioconjugate Vaccine Induces Functional Antibodies Reactive with Shigella Isolates from Kenya

mSphere, 2022
Diarrheal diseases are a leading cause of global morbidity and mortality, disproportionately affecting children in resource-limited settings. Although improvements in hygiene and access to clean water are helpful, vaccines are considered essential due to
Elizabeth A. Odundo, Hailey P. Weerts, Lillian Musila, Lilian Ogonda, Anita M. Dreyer, Joerg Schneider, Paula Carranza, Robert W. Kaminski   +7 more
doaj   +1 more source

CRISPR/Cas12a-Enhanced Loop-Mediated Isothermal Amplification for the Visual Detection of Shigella flexneri

Frontiers in Bioengineering and Biotechnology, 2022
Shigella flexneri is a serious threat to global public health, and a rapid detection method is urgently needed. The CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system is widely used in gene editing, gene ...
Yaoqiang Shi, Lan Kang, Rongrong Mu, Min Xu, X. Duan, Yujia Li, Chunhui Yang, Jia-wei Ding, Qinghua Wang, Shilin Li   +9 more
semanticscholar   +1 more source

Selection for Phage Resistance Reduces Virulence of Shigella flexneri

Applied and Environmental Microbiology, 2021
Shigella flexneri is a facultative intracellular pathogen of humans and a leading cause of bacillary dysentery. With few effective treatments and rising antibiotic resistance in these bacteria, there is increasing interest in alternatives to classical ...
K. Kortright, Rachel E. Done, B. Chan, V. Souza, P. Turner   +4 more
semanticscholar   +1 more source

Acid tolerance of Shigella sonnei and Shigella flexneri [PDF]

Journal of Applied Microbiology, 2002
Determination of the behaviour of Shigella sonnei and Sh. flexneri under acid conditions.The growth and survival of Shigella spp. (9 isolates) in acidified Brain Heart Infusion (BHI) (pH 5.0-3.25 with pH intervals of 0.25) was determined after 6, 24 and 30 h incubation at 37 degrees C.
C F, Bagamboula, M, Uyttendaele, J, Debevere   +2 more
openaire   +2 more sources

Lactoferrin-binding proteins in Shigella flexneri [PDF]

Infection and Immunity, 1992
The ability of Shigella flexneri to interact with lactoferrin (Lf) was examined with a 125I-labeled protein-binding assay. The percent binding of human lactoferrin (HLf) and bovine lactoferrin (BLf) to 45 S. flexneri strains was 19 +/- 3 and 21 +/- 3 (mean +/- standard error of the mean), respectively.
Z, Tigyi, A R, Kishore, J A, Maeland, A, Forsgren, A S, Naidu   +4 more
openaire   +2 more sources

Shigellosis and toxic megacolon secondary to Shigella flexneri serotype 3a: The challenges of laboratory diagnosis

International Journal of Infectious Diseases, 2018
We present a rare case of Shigella flexneri bacteraemia and toxic megacolon, and discuss the challenges of conventional laboratory techniques versus molecular PCR platforms in differentiating between Shigella species and Escherichia coli.
Emma McGuire, Simon Tiberi, Holly Ciesielczuk, Mark Melzer   +3 more
doaj   +1 more source

Identification of MHC Class II Immunopeptidomes from Shigella flexneri 2a-infected Macrophages as Potential Vaccine Candidates

Indonesian Biomedical Journal, 2022
BACKGROUND: Shigella is a Gram-negative rod-shaped intracellular bacterial pathogen that causes bacterial dysentery or shigellosis among children under five years old.
Nor Raihan Mohammad Shabani, Che Muhammad Khairul Hisyam Ismail, Chiuan Herng Leow, Munirah Mokhtar, Kirnpal Kaur Banga Singh, Chiuan Yee Leow   +5 more
doaj   +1 more source

Aktivitas Antibakteri Kulit Buah Karika Dieng terhadap Shigella flexneri dan Escherichia coli

Jurnal Teknologi Laboratorium, 2018
Karika merupakan tanaman endemik Dataran Tinggi Dieng. Daun Karika telah diteliti memiliki aktivitas antibakteri terhadap bakteri penyebab diare, sedangkan kulit buah dibuang atau dijadikan campuran pakan ternak. Penelitian ini bertujuan untuk mengetahui
Dhiah Novalina, Sugiyarto Sugiyarto, Ari Susilowati   +2 more
doaj   +1 more source

GMMA and Glycoconjugate Approaches Compared in Mice for the Development of a Vaccine against Shigella flexneri Serotype 6

Vaccines, 2020
Shigella infections are one of the top causes of diarrhea throughout the world, with Shigella flexneri being predominant in developing countries. Currently, no vaccines are widely available and increasing levels of multidrug-resistance make Shigella a ...
M. M. Raso, G. Gasperini, R. Alfini, Fabiola Schiavo, M. G. Aruta, M. Carducci, Maria Concetta Forgione, S. Martini, P. Cescutti, F. Necchi, F. Micoli   +10 more
semanticscholar   +1 more source

Keratitis Due to Shigella flexneri [PDF]

Journal of Clinical Microbiology, 2006
ABSTRACT Multiresistant Shigella flexneri isolates were cultured from the cornea and stool of a girl. Genetic analysis showed the isolates were identical. Shigella spp. are rare causes of ulcerative keratitis; there have only been 14 published cases since 1943.
Muytjens, H.L., Eggink, C.A., Dijkman, F.C.A.P., Bakkers, J.M.J.E., Melchers, W.J.G.   +4 more
openaire   +3 more sources