Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
, 2020 The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
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Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021 Background and Objectives: Today, because of the spread of drug resistance and the prevalence of infectious diseases, the use of medicinal plants has increased.
Marzieh An'aam +2 more
doaj
mBio, 2019 Two Shigella species, Shigella flexneri and Shigella sonnei, cause approximately 90% of bacterial dysentery worldwide. While S. flexneri is the dominant species in low-income countries, S.
Jayne L. Watson +6 more
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Biology and Life Sciences Forum, 2023 The sit-and-wait hypothesis predicts that bacterial durability in the external environment is positively correlated with the evolution of bacterial virulence.
Bin Gu +7 more
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Journal of Infection in Developing Countries, 2014 Introduction: This study was conducted to determine the prevalence of serotypes, virulence factors, and antimicrobial resistance patterns of Shigella spp. in Beijing, China, from 2004 to 2011.
Mei Qu +11 more
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The Multifaceted Activity of the VirF Regulatory Protein in the Shigella Lifestyle [PDF]
, 2016 Shigella is a highly adapted human pathogen, mainly found in the developing world and causing a severe enteric syndrome. The highly sophisticated infectious strategy of Shigella banks on the capacity to invade the intestinal epithelial barrier and cause ...
Colonna, Bianca +4 more
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Investigating the DNA-Binding Site for VirB, a Key Transcriptional Regulator of Shigella Virulence Genes, Using an In Vivo Binding Tool [PDF]
, 2019 The transcriptional anti-silencing and DNA-binding protein, VirB, is essential for the virulence of Shigella species and, yet, sequences required for VirB-DNA binding are poorly understood.
Karabachev, Alexander D. +6 more
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Clinical implications of reduced susceptibility to fluoroquinolones in paediatric Shigella sonnei and Shigella flexneri infections. [PDF]
, 2015 OBJECTIVES: We aimed to quantify the impact of fluoroquinolone resistance on the clinical outcome of paediatric shigellosis patients treated with fluoroquinolones in southern Vietnam.
Baker, Stephen +17 more
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Deletion of toxin–antitoxin systems in the evolution of Shigella sonnei as a host-adapted pathogen [PDF]
, 2016 Pathogenic Shigella spp. are the leading cause of bacterial dysentery, with Shigella flexneri and Shigella sonnei accounting for around 90% of cases worldwide. While S.
McVicker, G, Tang, CM
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The Rising Dominance of Shigella sonnei: An Intercontinental Shift in the Etiology of Bacillary Dysentery. [PDF]
, 2015 Shigellosis is the major global cause of dysentery. Shigella sonnei, which has historically been more commonly isolated in developed countries, is undergoing an unprecedented expansion across industrializing regions in Asia, Latin America, and the Middle
Baker, Stephen +2 more
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