Results 41 to 50 of about 54,989 (228)

tmRNA Is Essential in Shigella flexneri

open access: yesPLoS ONE, 2013
Nonstop mRNAs pose a challenge for bacteria, because translation cannot terminate efficiently without a stop codon. The trans-translation pathway resolves nonstop translation complexes by removing the nonstop mRNA, the incomplete protein, and the stalled ribosome.
Nitya S Ramadoss   +2 more
openaire   +4 more sources

Virulence factors and molecular characteristics of Shigella flexneri isolated from calves with diarrhea

open access: yesBMC Microbiology, 2020
Background The natural hosts of Shigella are typically humans and other primates, but it has been shown that the host range of Shigella has expanded to many animals. Although Shigella is becoming a major threat to animals, there is limited information on
Zhen Zhu   +7 more
semanticscholar   +1 more source

Dominant serotype distribution and antimicrobial resistance profile of Shigella spp. in Xinjiang, China.

open access: yesPLoS ONE, 2018
Shigella represents one of the major diarrhea-inducing pathogens threatening public health, but its prevalence and antimicrobial resistance profile in Xinjiang Uygur Autonomous region, China, remains unclear.
Hongbo Liu   +13 more
doaj   +1 more source

Exploring the Sit-and-Wait Potential of the Bacterial Pathogen Shigella flexneri: A Comparative Genomic Study

open access: yesBiology and Life Sciences Forum, 2023
The sit-and-wait hypothesis predicts that bacterial durability in the external environment is positively correlated with the evolution of bacterial virulence.
Bin Gu   +7 more
doaj   +1 more source

Characterization and immunogenicity of a Shigella flexneri 2a O-antigen bioconjugate vaccine candidate

open access: yesGlycobiology, 2019
Shigellosis remains a major cause of diarrheal disease in developing countries and causes substantial morbidity and mortality in children. Vaccination represents a promising preventive measure to fight the burden of the disease, but despite enormous ...
N. Ravenscroft   +14 more
semanticscholar   +1 more source

GBPs Inhibit Motility of Shigella flexneri but Are Targeted for Degradation by the Bacterial Ubiquitin Ligase IpaH9.8

open access: yesCell Host and Microbe, 2017
Summary Interferon exposure boosts cell-autonomous immunity for more efficient pathogen control. But how interferon-enhanced immunity protects the cytosol against bacteria and how professionally cytosol-dwelling bacteria avoid clearance are ...
M. Wandel   +7 more
semanticscholar   +1 more source

Finding potential drug targets against Shigella flexneri through druggable proteome exploration.

open access: yesFrontiers in Microbiology, 2016
:Background: Shigella flexneri is a gram negative bacteria that causes the infectious disease ‘shigellosis’. Shigella flexneri (S. flexneri) is responsible for developing diarrhea, fever and stomach cramps in human.
Mohammad Uzzal Hossain   +6 more
doaj   +1 more source

Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model

open access: yesInfection and Immunity, 2019
The enteric pathogen Shigella is one of the leading causes of moderate-to-severe diarrhea and death in young children in developing countries. Transformed cell lines and animal models have been widely used to study Shigella pathogenesis.
S. Ranganathan   +5 more
semanticscholar   +1 more source

A murine model of diarrhea, growth impairment and metabolic disturbances with Shigella flexneri infection and the role of zinc deficiency

open access: yesGut microbes, 2019
Shigella is one of the major enteric pathogens worldwide. We present a murine model of S. flexneri infection and investigate the role of zinc deficiency (ZD).
Pedro Henrique Q S Medeiros   +11 more
semanticscholar   +1 more source

Phytochemical content, antioxidant and antibacterial properties of Typhonium flagelliforme cultivated via soil and hydroponic methods

open access: yesJSFA reports, EarlyView.
Abstract Background Typhonium flagelliforme is a medicinal herb in the Araceae family, widely distributed in Southeast Asia. This study aimed to evaluate the effects of hydroponic and soil‐based cultivation systems on the phytochemical content and bioactivity of T. flagelliforme. Results Using liquid chromatography‐mass spectrometry (LC‐MS) analysis, 9
Yen Ning Lee   +4 more
wiley   +1 more source

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