Results 11 to 20 of about 15,710 (211)
Population Pharmacokinetic and Pharmacodynamic Prediction for Tebipenem Pivoxil Treatment of Pediatric Shigellosis. [PDF]
ABSTRACT Increasing antimicrobial resistance poses a serious challenge for the treatment of Shigella infections, and there is an urgent need for alternative antibacterial treatments. We conducted a clinical trial to investigate the efficacy of oral tebipenem pivoxil, compared to intravenous ceftriaxone, in Bangladeshi children with shigellosis.
Zhang CX +12 more
europepmc +2 more sources
Shigellaa Gram-negative, non-motile bacillus, is the primary causative agent of the infectious disease shigellosis, which kills 1.1 million people worldwideevery year. The children under the age of five are primarily the victims of this disease.
A K M Zakir Hossain +4 more
doaj +1 more source
Background Shigella causes approximately 500,000 illnesses, 6000 hospitalizations, and 40 deaths in the United States annually, but incidence and populations at risk for severe shigellosis among adults are unclear. This study describes severe shigellosis
Lindsey S. McCrickard +3 more
doaj +1 more source
Objective: In China, the burden of shigellosis is unevenly distributed, notably across various ages and geographical areas. Shigellosis temporal trends appear to be seasonal. We should clarify seasonal warnings and regional transmission patterns. Method:
Zeyu Zhao +15 more
doaj +1 more source
Epidemiology of Shigella-Associated diarrhea in Gorgan, north of Iran [PDF]
Objective : Shigella is an important etiological agent for diarrhea and especially dysentery. Shigellosis is an intestinal infection that is a major public health problem in many developing countries.
Ahmadi, A.R. +7 more
core +1 more source
HIV Infection as a Risk Factor for Shigellosis
We investigated cases of shigellosis in San Francisco and Alameda Counties identified during 1996 by active laboratory surveillance to assess the role of HIV infection as a risk factor for shigellosis.
Jefferson T. Baer +5 more
doaj +1 more source
A retrospective analysis of Shigellosis in hospitalized patients
The relevance of the study of Shigellosis is due to the fact that the pathogen is capable of invasion and the production of cyto- and neurotoxins, which leads to the development of severe inflammation and toxicosis, and with massive infection — and ...
O. V. Molochkova +8 more
doaj +1 more source
Characterization of an emergent clone of enteroinvasive Escherichia coli circulating in Europe [PDF]
Enteroinvasive Escherichia coli (EIEC) cause intestinal illness indistinguishable from that caused by Shigella, mainly in developing countries. Recently an upsurge of cases of EIEC infections has been observed in Europe, with two large outbreaks ...
Caprioli, A. +9 more
core +1 more source
Emergence of antibiotic resistant Shigella species: A matter of concern
A major threat to the world is the emergence of antibiotic resistant bacteria, which has rendered previously susceptible drugs useless and increased the rate of therapeutic failures. Shigella species, which are the causative organism of Shigellosis, were
Minakshi Puzari +2 more
doaj +1 more source
Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe [PDF]
Shigella are human-adapted Escherichia coli that have gained the ability to invade the human gut mucosa and cause dysentery1,2, spreading efficiently via low-dose fecal-oral transmission3,4. Historically, S.
A Mutreja +55 more
core +4 more sources

