Results 161 to 170 of about 985,996 (219)

Engineering the Biosynthesis of Daidzein and Genistein with the Red Oleaginous Yeast <i>Rhodotorula toruloides</i>. [PDF]

ACS Omega
Huang Y, Gao Q, Dong Y, Wang Y, Wang X, Yang X.   +5 more
europepmc   +1 more source

Seasonal changes in the physiology and metabolism of grapevine latent buds. [PDF]

J Exp Bot
Signorelli S, Velappan Y, Hermawaty D, Feil R, Couture C, Considine JA, Lunn JE, Considine MJ.   +7 more
europepmc   +1 more source

Insights into the proteome of next-generation probiotic Faecalibacterium duncaniae A2-165 through label-free proteomics approach. [PDF]

BMC Microbiol
Ferrary Américo M, Vilela Rodrigues T, Henry C, Marques da Silva W, Verano-Braga T, Azevedo V, Chatel JM.   +6 more
europepmc   +1 more source

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An overview of mechanism and chemical inhibitors of shikimate kinase

Journal of Biomolecular Structure and Dynamics, 2023
Tuberculosis is a highly infectious disease other than HIV/AIDS and it is one of the top ten causes of death worldwide. Resistance development in the bacteria occurs because of genetic alterations, and the molecular insights suggest that the accumulation
Bharath Kumar Chagaleti, M. Reddy, Venkatesan Saravanan, S. B., P. D., P. Senthil Kumar, M. Kathiravan   +6 more
semanticscholar   +3 more sources

Toxicological Profiling of Potential Shikimate Kinase Inhibitors Against Mycobacterium tuberculosis

Alternatives to Laboratory Animals, 2023
Over the last decade, Mycobacterium tuberculosis has mutated into a putative ‘superbug’, as treatments against it have failed due to increasing antimicrobial resistance.
Ashish Jhangiani, Vandana Panda, Aanchal Sukheja, S. Thomas, Piyush Dusseja, Siddharth Pandya, Anand Chintakrindi   +6 more
semanticscholar   +3 more sources

Shikimate Kinase; Searching for Potential Novel Anti‐Tubercular Agents

The FASEB Journal, 2022
Tuberculosis is a respiratory infection with over 10 million reported cases each year. This infection rate is responsible for over two million deaths annually, second only to HIV in fatalities among infectious diseases annually.
Marcin Ogrodniczuk, René Fuanta
semanticscholar   +2 more sources

Identification of novel scaffold using ligand and structure based approach targeting shikimate kinase.

Bioorganic Chemistry, 2020
Tuberculosis (TB) remains a major global health problem. It causes ill-health among millions of people each year and rank as the second leading cause of death from an infectious disease worldwide, after the human immunodeficiency virus (HIV).
M. B. Rahul Reddy, S. Krishnasamy, M. Kathiravan   +2 more
semanticscholar   +3 more sources

Shikimate kinase inhibitors: An update on promising strategy against Mycobacterium tuberculosis.

Current Drug Targets, 2023
Humanity has been battling with tuberculosis (TB) for a long period, and despite the availability of drugs well-known to act against the deadly microbe, the menace is still very far from reaching its end.
V. Rajput, Ashish Runthala, I. Khan
semanticscholar   +3 more sources

Mechanism of Phosphoryl Transfer Catalyzed by Shikimate Kinase from Mycobacterium tuberculosis

Journal of Molecular Biology, 2006
The structural mechanism of the catalytic functioning of shikimate kinase from Mycobacterium tuberculosis was investigated on the basis of a series of high-resolution crystal structures corresponding to individual steps in the enzymatic reaction. The catalytic turnover of shikimate and ATP into the products shikimate-3-phosphate and ADP, followed by ...
Marcus D Hartmann
exaly   +5 more sources