Results 151 to 160 of about 14,122 (212)
Cinnamon Bud Extract Is a Source of Biomolecules Active against the Aggregation and Condensation of Alzheimer's-Associated Tau Protein. [PDF]
Viola G +7 more
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Computational investigation of African natural products as Helicobacter pylori shikimate kinase inhibitors. [PDF]
Sharma Paudel HR.
europepmc +1 more source
Early occurrence of caffeoylshikimic acid esterase (CSE) activity in the hornwort Anthoceros agrestis. [PDF]
Marks J, Petersen M.
europepmc +1 more source
Breeding of glyphosate-tolerant genetically modified rice BriA15-38. [PDF]
Yang J +4 more
europepmc +1 more source
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Biotechnology Advances, 2012
Shikimic acid is a key intermediate for the synthesis of the antiviral drug oseltamivir (Tamiflu®). Shikimic acid can be produced via chemical synthesis, microbial fermentation and extraction from certain plants. An alternative production route is via biotransformation of the more readily available quinic acid.
Saptarshi, Ghosh +2 more
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Shikimic acid is a key intermediate for the synthesis of the antiviral drug oseltamivir (Tamiflu®). Shikimic acid can be produced via chemical synthesis, microbial fermentation and extraction from certain plants. An alternative production route is via biotransformation of the more readily available quinic acid.
Saptarshi, Ghosh +2 more
openaire +4 more sources
Nature, 1955
IN a paper describing, inter alia, the isolation of quinic acid from grass1, it was suggested that one of the acids (termed ‘acid B’) present in the grass extracts might be shikimic acid or a closely allied acid. Acid B appeared to be identical with ‘acid G’ found by Davies and Hughes2 in grass and stated by them to be a monobasic acid of relatively ...
A. RICHARDSON, A. C. HULME
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IN a paper describing, inter alia, the isolation of quinic acid from grass1, it was suggested that one of the acids (termed ‘acid B’) present in the grass extracts might be shikimic acid or a closely allied acid. Acid B appeared to be identical with ‘acid G’ found by Davies and Hughes2 in grass and stated by them to be a monobasic acid of relatively ...
A. RICHARDSON, A. C. HULME
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Production and Synthetic Modifications of Shikimic Acid
Chemical Reviews, 2018Shikimic acid is a natural product of industrial importance utilized as a precursor of the antiviral Tamiflu. It is nowadays produced in multihundred ton amounts from the extraction of star anise ( Illicium verum) or by fermentation processes. Apart from the production of Tamiflu, shikimic acid has gathered particular notoriety as its useful carbon ...
Nuno R. Candeias +2 more
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Hydroaromatic Equilibration During Biosynthesis of Shikimic Acid
Journal of the American Chemical Society, 2001The expense and limited availability of shikimic acid isolated from plants has impeded utilization of this hydroaromatic as a synthetic starting material. Although recombinant Escherichia coli catalysts have been constructed that synthesize shikimic acid from glucose, the yield, titer, and purity of shikimic acid are reduced by the sizable ...
D R, Knop +6 more
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Enantiospecific synthesis of (−)-5-epi-shikimic acid and (−)-shikimic acid
Journal of the Chemical Society, Perkin Transactions 1, 1997Diastereoselective reaction of 2,3-O-isopropylidene-D-ribose with allylmagnesium chloride gave a 5∶1 mixture of triols 4 and 5, which were then converted to nitrones 8 and 9. Intramolecular nitrone cycloaddition gave the isoxazolidines 10 and 11, which on acetylation gave the corresponding acetates 12 and 13 which were separated by repeated ...
Shende Jiang +4 more
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