Results 161 to 170 of about 14,009 (216)

Colorimetric assay of shikimic acid against quinic acid

Analytical Biochemistry, 1972
Abstract Shikimic acid heated with p-hydroxybenzaldehyde and concentrated sulfuric acid produces an intense and stable purple-violet dye with absorption maximum at 590 nm, and can be quantitatively determined in the range from 15 to over 120 ng (0.1 to 0.7 μmole/ml). Under the same conditions quinic acid produces no color reaction. Shikimic acid can
T, Mossor, R W, Schramm
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Shikimic Acid Pathway: Phenols

2023
Plant metabolites having one or more hydroxyl groups attached to an aromatic ring are known as phenols. Phenols are a heterogeneous group of compounds. One of the most important functions of phenols is in plant communication e.g., allelopathy, attracting pollinating and disseminating agents, attracting symbiotic bacteria, and inhibiting pathogens and ...
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A thiobarbituric acid assay for shikimic acid

Analytical Biochemistry, 1963
Abstract A sensitive and easily reproducible colorimetric assay has been developed for shikimic acid based on periodate oxidation in concentrated phosphoric acid. The periodate oxidation product reacts with thiobarbituric acid to produce a stable chromogen which, when extracted into cyclohexanone, has an absorption maximum at 535 mμ and an apparent ...
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Shikimic Acid Pathway Metabolites

1981
Benzenoid compounds in plants are biosynthesised by two main pathways: the shikimic acid pathway and the acetate-malonate pathway (Chapter 4). In higher plants, a large number of aromatic compounds are derived from phenylalanine, tyrosine and tryptophan, end-products of the shikimic acid pathway.
Margaret L. Vickery, Brian Vickery
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Difluorinated analogues of shikimic acid

Tetrahedron, 2003
Investigations into the quinate to shikimate transformation have been carried out, the results of which have been exploited in the synthesis of a novel difluoromethylene homologue of shikimic acid from (-)-quinic acid. Martin's sulfurane {Ph2S[OC(CF3)2Ph]2} was the reagent of choice for the key dehydration step of this synthesis.
Begum, Lovely, Box, Julian M., Drew, Michael G B, Harwood, Laurence M., Humphreys, Jane L., Lowes, David J., Morris, Gareth A., Redon, Perrine M., Walker, Francine M., Whitehead, Roger C.   +9 more
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Hydroaromatic Equilibration During Biosynthesis of Shikimic Acid

Journal of the American Chemical Society, 2001
The expense and limited availability of shikimic acid isolated from plants has impeded utilization of this hydroaromatic as a synthetic starting material. Although recombinant Escherichia coli catalysts have been constructed that synthesize shikimic acid from glucose, the yield, titer, and purity of shikimic acid are reduced by the sizable ...
D R, Knop, K M, Draths, S S, Chandran, J L, Barker, R, von Daeniken, W, Weber, J W, Frost   +6 more
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Five-Membered Ring Analogues of Shikimic Acid

The Journal of Organic Chemistry, 2001
Shikimate and other intermediates of the shikimate-chorismate pathway are densely functionalized structures that seem to offer limited options for skeletal modification. We designed and synthesized cyclopentylidenes 1 and 2, as well as cyclopentenes 3 and 4, as novel ring-contracted analogues of shikimic acid.
M, An, T, Toochinda, P A, Bartlett
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Production and Synthetic Modifications of Shikimic Acid

Chemical Reviews, 2018
Shikimic acid is a natural product of industrial importance utilized as a precursor of the antiviral Tamiflu. It is nowadays produced in multihundred ton amounts from the extraction of star anise ( Illicium verum) or by fermentation processes. Apart from the production of Tamiflu, shikimic acid has gathered particular notoriety as its useful carbon ...
Nuno R. Candeias, Benedicta Assoah, Svilen P. Simeonov   +2 more
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Interaction of shikimic acid with shikimate kinase.

Biochemical and biophysical research communications, 2005
The crystal structure of shikimate kinase from Mycobacterium tuberculosis (MtSK) complexed with MgADP and shikimic acid (shikimate) has been determined at 2.3A resolution, clearly revealing the amino acid residues involved in shikimate binding. In MtSK, the Glu61 strictly conserved in SK forms a hydrogen bond and salt-bridge with Arg58 and assists in ...
José Henrique, Pereira, Jaim Simões, de Oliveira, Fernanda, Canduri, Marcio Vinicius Bertacine, Dias, Mário Sérgio, Palma, Luiz Augusto, Basso, Walter Filgueira, de Azevedo, Diógenes Santiago, Santos   +7 more
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Enantiospecific synthesis of (-)-5-epi-shikimic acid and a new route to (-)-shikimic acid

Tetrahedron Letters, 1994
Abstract (-)-Shikimic acid ( 1 ) and (-)-5- epi -shikimic acid ( 2 ) have each been prepared enantiospecifically and with high diastereoselectivity from D-ribose.
Shende Jiang, Boualem Mekki, Gurdial Singh, Richard H. Wightman   +3 more
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