Results 121 to 130 of about 13,920 (304)

Population pharmacokinetics of levofloxacin in breastmilk in patients with rifampicin‐resistant tuberculosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Levofloxacin is a widely used antibiotic included in rifampicin‐resistant tuberculosis (RR‐TB) treatment. Data describing levofloxacin concentrations in breastmilk and infant exposure are limited. We analysed data from two South African studies of breastfeeding women receiving levofloxacin (750–1000 mg daily) for RR‐TB.
Sharon Sawe   +9 more
wiley   +1 more source

A dose‐finding population pharmacokinetic/pharmacodynamic model of ginisortamab, an anti‐gremlin‐1 monoclonal antibody, in patients with solid tumours

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ginisortamab, a first‐in‐class human monoclonal antibody for the treatment of advanced solid tumours, binds to gremlin‐1 and restores bone morphogenetic protein signalling. We used pharmacokinetic/pharmacodynamic (PK/PD) modelling to characterize the relationship between ginisortamab dose and serum gremlin‐1 binding, using model‐based simulations ...
Yin Cheong Wong   +6 more
wiley   +1 more source

A Study on efficiency of maritime education and training by Ship handling simulater [PDF]

open access: yes
Most of marine casualties are caused by not only wrong operation of equipments but also lack of knowledge about navigational equipments or systems. But we can say these casualties result from their mental problem or lack of situational awareness.
정낙영
core  

How do secondary schools in England talk about modern languages? A corpus‐assisted discourse analysis of school websites

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Situating the study within an ecological perspective on language education, this article examines how secondary schools in England present Modern Languages (MLs) on official school websites. Focusing on 44 schools in Local Authorities with the lowest percentage average entry for the Languages pillar of the EBacc, we built a text database ...
Zhu Hua, Yunpeng Du, Elin Arfon
wiley   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner   +7 more
wiley   +1 more source

A roadmap to key traits of invasive Drosophilidae

open access: yesBiological Reviews, EarlyView.
ABSTRACT Biological invasions have intensified in recent decades, mostly driven by international trade and travel, raising significant concerns, particularly regarding insect pests. Once non‐native species establish, they can disrupt natural ecosystem stability, undermine agroecosystem sustainability and cause substantial economic losses.
Gwenaëlle Deconninck   +14 more
wiley   +1 more source

S-CVX: A Short Take-off/Vertical Landing (STOVL) Aircraft Carrier

open access: yes, 1997
Web page capture of TSSE Team 1997 - S-CVX: A Short Take-off/Vertical Landing (STOVL) Aircraft Carrier project page, as it appeared July 2, 2025.In the era since World War II, the aircraft carrier has continued to play the role of the central element in ...

core  

Circular Design Strategies Unleashed: Competitiveness and the Journey Towards Circular Manufacturing Businesses

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The transition to a circular economy (CE) remains hindered by the lack of practical strategies that simultaneously secure competitiveness and deliver sustainability outcomes for manufacturing organisations. While circular design is often cited as a cornerstone of CE, its concrete role in driving competitive advantage and organisational ...
Shamaila Ishaq   +3 more
wiley   +1 more source

Innovative Fast Time Simulation Tools for Briefing / Debriefing in Advanced Ship Handling Simulator Training and Ship Operation

open access: yes, 2017
The innovative “Simulation-Augmented Manoeuvring Design, Monitoring & Control” system (SAMMON) based on Fast Time Simulation (FTS) technology was developed at the Institute for Innovative Ship Simulation and Maritime Systems (ISSIMS) of the Maritime ...
Sandro Fischer   +13 more
core   +1 more source

Resource‐Centered Transformation Paths: The Role of Digital Transformation in Optimizing SME Resources for Sustainable Entrepreneurship

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The critical role of small and medium‐sized enterprises (SMEs) in driving economic growth through employment generation and innovation cannot go unseen, especially the efforts of small firms in promoting sustainable entrepreneurship. With more market and consumer focus on sustainability and the shift toward eco‐friendly products, SMEs can ...
Nasser Hadi Alajmi
wiley   +1 more source

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