Results 21 to 30 of about 15,373 (255)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

A Treatise on the Stability of Ships

Nature, 2010
Sir Edward James Reed (1830–1906) was appointed chief constructor of the Navy in 1863, and later founded his own ship design consultancy. He pioneered the methodical use of scientific calculations to determine a ship's weight, strength and stability, and was responsible for a number of revolutionary designs at a crucial period, when ships began to be ...
openaire   +3 more sources

Platform Monitoring Berbasis Web untuk Sistem Stabilitas dan Pelacakan Kapal Nelayan

Digital Zone: Jurnal Teknologi Informasi dan Komunikasi, 2023
Fishing activities in the waters of Bengkalis Island face a number of serious problems, including a lack of data during fishing activities and ship accidents caused by delays in information.
Agus Tedyyana, Fajar Ratnawati, Danuri Danuri   +2 more
doaj   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source

Engagement Patterns with an AI Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, Accepted Article.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed‐methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

Research on safety evaluation and weather routing optimization of ship based on roll dynamics and improved A* algorithm

International Journal of Naval Architecture and Ocean Engineering
With the steady growth of international trade, sea transport has become indispensable, leading to an increase in maritime accidents. The sinking of the Russian Black Sea Fleet flagship, the guided missile cruiser “Moskva,” underscores the critical need ...
Zilong Guo, Mei Hong, Yongchui Zhang, Jian Shi, Longxia Qian, Hanlin Li   +5 more
doaj   +1 more source

Karl Popper and the Mechanisms of Hydrogen Embrittlement

Advanced Engineering Materials, EarlyView.
Representation of the beginning of loss of ductility rather than embrittlement. Small concentrations of hydrogen in a diffusible form within iron are well‐established to harm the mechanical integrity of steels. There are theories that attempt to explain the pernicious role of hydrogen.
H. K. D. H. Bhadeshia
wiley   +1 more source

New Generation Stability Norms – How to Approach the Task

Polish Maritime Research, 2018
International stability norms included in the Code of Intact Stability 2008 adopted by IMO on 4 December 2008 constitutes the latest set of international requirements on intact stability of ships.
Kobyliński Lech
doaj   +1 more source

Conditions of using floating cranes for lifting sunken objects on inland waterways [PDF]

Vojnotehnički Glasnik, 2012
This paper presents the conditions for using floating cranes for lifting sunken vessels and other objects on inland waterways. Basic technical data are given together with technical details for the usage of floa ting cranes for lifting sunken objects ...
Slobodan M. Radojević
doaj   +1 more source