Results 91 to 100 of about 22,720 (264)

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

open access: yesAdvanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett   +19 more
wiley   +1 more source

Artery‐on‐Chip Demonstrates Mechanical and Functional Features of Healthy and Diseased Living Smooth Muscle Tissue

open access: yesAdvanced Functional Materials, EarlyView.
This article details the development of an artery‐on‐chip platform for in vitro arterial disease modeling and therapeutic discovery. It describes the fabrication of a fibrin biomaterial scaffold seeded with iPSC‐derived smooth muscle and endothelial cells, mimicking native artery properties. Two genetic disease models showcase the platform's ability to
Danielle Yarbrough   +10 more
wiley   +1 more source

Myrcene‐Based Tailored Co‐Polymers as Active Pharmaceutical Excipients: Bio‐Based Solutions for Mucoadhesive Excipients

open access: yesAdvanced Functional Materials, EarlyView.
Mucoadhesive amphiphilic block and statistical copolymers were synthesized via Reversible Addition–Fragmentation Chain Transfer polymerization from bio‐sourced myrcene and polyethylene glycol methacrylate. The resulting polymers exhibit narrow molar‐mass distributions, high regioselectivity, well‐defined microstructures, and tend to self‐assemble into ...
David Gintsburg   +9 more
wiley   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

open access: yesAdvanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho   +8 more
wiley   +1 more source

Chemical Maturation Controls Bioavailability of Fetuin‐A‐Mineral Complexes in Biomineralization

open access: yesAdvanced Functional Materials, EarlyView.
The role of Fetuin‐A‐mineral complexes in matrix mineralization is unclear. Here, Fetuin‐A‐mineral complexes were found to exist in functionally distinct states that determine mineral bioavailability: chemically labile calciprotein monomers directly mineralize collagen fibrils, while chemically matured primary calciprotein particles require cellular ...
Judith M. Schaart   +8 more
wiley   +1 more source

A Comparative Study on the Effect of Intravenous Hydrocortisone and Ketamine on Reducing Shivering after Spinal Anesthesia in Cesarean Section: A Double-blind Randomized Controlled Trial

open access: yesArchives of Anesthesia and Critical Care, 2018
Background: Shivering is rhythmic vibratory motions in one or more group of muscle that caused after general or local anesthesia. Prevention and early treatment of Shivering lead to not conflict with patient monitoring and also reduce cardio-respiratory ...
Nahid Manouchehrian   +4 more
doaj  

Electrostatic‐Attraction‐Driven Self‐Assembled Graphene‐Disordered Rocksalt Composite Cathode for Lithium‐Ion Batteries

open access: yesAdvanced Functional Materials, EarlyView.
A non‐aqueous, solution‐based graphene‐wrapping strategy is shown to stabilize disordered rocksalt LMTOF cathodes without structural degradation. The graphene‐wrapped cathode suppresses oxygen loss and parasitic interfacial reactions, lowers impedance growth, and delivers improved cycling stability and rate capability compared with conventional ball ...
Venkata Sai Avvaru   +14 more
wiley   +1 more source

High‐Efficiency PFOA Removal by Microstructure‐Engineered Ultrathin Amphiphilic Mesoporous Reduced Graphene Oxide@Silica

open access: yesAdvanced Functional Materials, EarlyView.
This study developed an amphiphilic ultrathin mesoporous adsorbent through microstructure design, which exhibits remarkable mass transport efficiency and high affinity toward PFAS, thereby achieving an ultrahigh uptake capacity and rapid kinetics for PFAS adsorption.
Yeqiu Zhao   +11 more
wiley   +1 more source

Dexamethasone for prevention of postoperative shivering: A randomized double-blind comparison with pethidine

open access: yesInternational Journal of Preventive Medicine, 2013
Background: Postoperative shivering is very common and followed by many problems such as increasing oxygen consumption, blood pressure, intracranial and intraocular pressure, and postoperative pain.
Masood Entezariasl, Khatereh Isazadehfar
doaj  

Graphene Quantum Dot‐Induced Microstrain for Framework Stabilization of High‐Entropy Prussian Blue Analog in High‐Current Alkaline Hydrogen Evolution Reaction

open access: yesAdvanced Functional Materials, EarlyView.
The intrinsic distortion‐rich lattice of HEPBA with GQD‐enabled microstrain engineering establishes a mechanistic route toward high‐performance alkaline hydrogen evolution reaction. HEPBA inherently feature heterogeneous local coordination environments arising from multimetal incorporation, while properly introducing GQD during coprecipitation ...
Mia Rinawati   +10 more
wiley   +1 more source

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