This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister +14 more
wiley +1 more source
Comparing warming strategies to reduce hypothermia and shivering in elderly abdominal or pelvic surgery patients: a network meta-analysis. [PDF]
Zheng W, Huang B, Bao L, Wang J, Jin J.
europepmc +1 more source
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold +9 more
wiley +1 more source
Anti-shivering Drug Influences the Characteristics of Electroencephalographic Shivering Noise During Targeted Temperature Management: A Case Report. [PDF]
Honda H, Nishiyama K.
europepmc +1 more source
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang +13 more
wiley +1 more source
Comparison of Perioperative Single-Dose Systemic Dexamethasone Versus Placebo for Prolongation of Postoperative Analgesia in Term Parturients Undergoing Cesarean Section Under Spinal Anesthesia. [PDF]
Ravishankar N +2 more
europepmc +1 more source
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij +8 more
wiley +1 more source
Prevention of shivering post spinal anesthesia: Ondansetron vs. Nefopam ‒ a prospective randomized controlled trial. [PDF]
Tohme J +7 more
europepmc +1 more source
Adhesions’ high occurrence rates and high morbidity render them a critical challenge to be addressed. Current prevention methods, such as physical barriers, have many limitations, resulting in inconsistent safety and efficacy. This study demonstrates the potential for sprayable polymeric materials as an adhesion barrier.
Robert J. Morris III +7 more
wiley +1 more source
Effect of epidural dexmedetomidine on post-operative nausea & vomiting in adult patients undergoing abdominopelvic surgery: a randomized controlled study. [PDF]
Koopredechat P +5 more
europepmc +1 more source

